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Comparative Study of Changpo(Ch$\={a}$ngp$\'{u}$) species on Antioxidant Activity and HPLC Pattern Analysis

4종 창포류의 성분 패턴 및 항산화 효능 비교

  • Choi, Go-Ya (Creative Research Team, Korea Institute of Oriental Medicine) ;
  • Ko, Byoung-Seob (Creative Research Team, Korea Institute of Oriental Medicine) ;
  • Lee, Mi-Young (Creative Research Team, Korea Institute of Oriental Medicine) ;
  • Chae, Sung-Wook (Creative Research Team, Korea Institute of Oriental Medicine) ;
  • Kim, Young-Hwa (Creative Research Team, Korea Institute of Oriental Medicine) ;
  • Ryuk, Jin-Ah (Creative Research Team, Korea Institute of Oriental Medicine) ;
  • Baek, Ji-Seong (Department of Herbology, College of Oriental Medicine, Woosuk University) ;
  • Lee, Hye-Won (Creative Research Team, Korea Institute of Oriental Medicine)
  • 최고야 (한국한의학연구원 창의연구실) ;
  • 고병섭 (한국한의학연구원 창의연구실) ;
  • 이미영 (한국한의학연구원 창의연구실) ;
  • 채성욱 (한국한의학연구원 창의연구실) ;
  • 김영화 (한국한의학연구원 창의연구실) ;
  • 육진아 (한국한의학연구원 창의연구실) ;
  • 백지성 (우석대학교 한의과대학 본초방제학교실) ;
  • 이혜원 (한국한의학연구원 창의연구실)
  • Received : 2011.02.14
  • Accepted : 2011.03.10
  • Published : 2011.03.30

Abstract

Objective : This study was to compare antioxidant activity and HPLC pattern analysis from 4 species of changpo(ch$\={a}$ngp$\'{u}$). Methods : To compare the antioxidant activity and HPLC pattern analysis from the 4 species of changpo, we performed the in vitro anti-oxidative activity assays and HPLC analysis from 70% ethanol extracts of Acorus gramineus Sol. (=AG), A. tatarinowii Schott (=AT), A. calamus L. (=AC) and Anemone altaica Fisch. ex C.A.Mey (=AA) taken in the herbal medicine market of Korea. Results : AG has the most effective anti-oxidative activity among 4 species of changpo. As the HPLC pattern analysis, AT was detected the unknown peak at retention time 14.9 min whereas AG was not showed any peak at the same retention time. These results suggest that AG could be used rather than AT when it need to be prescribed as anti-oxidative medicine. Conclusions : This result can be used as the basic data contributing to the stability of AG according to an appropriate clinical application.

Keywords

References

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