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Relationship Between Fatty Liver and Coronary Risk Factors among Health Examined Adult Women in an University Hospital

한 대학병원 건강검진센터에 내원한 성인 여성의 지방간과 관상동맥질환위험인자와의 관련성

  • Lee, Kwang-Sung (Department of Radiological Techniology, Daejeon Health Science College) ;
  • Park, Jae-Young (Department of Physical Therapy, College of Health Welfare, Kyungwoon University) ;
  • Cho, Young-Chae (Department of Preventive Medicine and Public Health, Chungnam National University School of Medicine and Research Institute for Medical Sciences)
  • 이광성 (대전보건대학 방사선과) ;
  • 박재영 (경운대학교 보건복지대학 물리치료과) ;
  • 조영채 (충남대학교 의학전문대학원 예방의학교실 및 의학연구소)
  • Received : 2011.05.17
  • Accepted : 2011.07.07
  • Published : 2011.07.31

Abstract

The present study was to elucidate such a relationship by comparing the coronary risk factors with and without fatty liver adjusted for age and/or BMI. Study subjects were 665 women of 30 years and over, who underwent health package check-up at the health promotion center of an university hospital from July, 2009 to June, 2010. As a results, the prevalence rates of fatty liver of study subjects were 11.6%, and the rates were significantly higher in older age group, in the group of higher level of BMI. The group of subjects with fatty liver had significantly lower mean HDL-cholesterol and higher levels of body fat rate, TG, TC, LDL-cholesterol, FBS and ALT, then those parameters in subjects without fatty liver, even after adjustment for age and/or BMI. In age and BMI adjusted logistic regressions, The odds ratio of fatty liver was increased significantly as there is an increase in the abnormal group with TG, TC, LDL-C and ALT.

본 연구는 복부초음파검사를 통하여 얻은 건강진단 결과로부터 지방간의 유소견자 비율을 파악하고, 지방간이 어느 정도 관상동맥질환위험인자와 관련하고 있는가를 검토하는 것을 목적으로 2009년 7월부터 2010년 6월까지의 기간에 한 대학병원 건강검진센터에서 종합건강검진을 받았던 30세 이상 여성 665명을 대상으로 하였다. 연구결과 전체 조사대상 여성의 지방간 유소견율은 11.6%이었으며, 저연령군보다 고연령군에서, 비만도가 증가할수록, 유소견율은 유의하게 증가하였다. 연령과 BMI를 보정한 상태에서의 체지방율, 중성지질, 총콜레스테롤, LDL-콜레스테롤, 공복시 혈당 및 ALT는 지방간군이 비지방간군보다 유의하게 높았으며, HDL-콜레스테롤은 비지방간군이 지방간군보다 유의하게 높았다. 연령과 BMI를 조정한 관상동맥질환위험인자와 혈액 검사치에 따른 지방간의 위험비는 TG, TC, LDL-C 및 ALT치가 정상군보다 비정상군에서 유의하게 높게 나타났다.

Keywords

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