Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Collagen Increasing and Hair Growth Effect of Supramolecular Cosmetic Materials Containing Phytochemicals

식물성 유용물질을 함유하는 초분자체 화장제재의 콜라겐 증가 및 육모효과

  • Cho, Hyun-Nam (Department of Applied Chemistry, Kumoh National Institute of Technology) ;
  • Yoo, Dong-Chan (Department of Applied Chemistry, Kumoh National Institute of Technology) ;
  • Kim, Kyoung-Ran (Department of Applied Chemistry, Kumoh National Institute of Technology) ;
  • Byun, Hae-Jung (Department of Applied Chemistry, Kumoh National Institute of Technology) ;
  • Kim, Jung-Hyun (Department of Applied Chemistry, Kumoh National Institute of Technology) ;
  • Park, Hye-Bin (Department of Applied Chemistry, Kumoh National Institute of Technology) ;
  • Bang, Dae-Suk (Department of Polymer Science and Engineering, Kumoh National Institute of Technology) ;
  • Yang, Seun-Ah (Center for Traditional Microorganism Resources (TMR), Keimyung University) ;
  • Khang, Gong-Won (LATIV CO., Ltd.) ;
  • Jhee, Kwang-Hwan (Department of Applied Chemistry, Kumoh National Institute of Technology)
  • 조현남 (금오공과대학교 응용화학과) ;
  • 유동찬 (금오공과대학교 응용화학과) ;
  • 김경란 (금오공과대학교 응용화학과) ;
  • 변혜정 (금오공과대학교 응용화학과) ;
  • 김정현 (금오공과대학교 응용화학과) ;
  • 박혜빈 (금오공과대학교 응용화학과) ;
  • 방대석 (금오공대 고분자공학과) ;
  • 양선아 (계명대학교 전통미생물자원개발 및 산업화 연구(TMR)센터) ;
  • 강공원 ((주)라티브) ;
  • 지광환 (금오공과대학교 응용화학과)
  • Received : 2012.01.11
  • Accepted : 2012.03.09
  • Published : 2012.03.30
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Abstract

Medicinal herbs have been shown to have protective functions for skin and hair. We investigated the effects of complex of soluble ${\beta}$-cyclodextrin and phytochemicals on the functions of skin and hair. In previous report, we evaluated the safety of supramolecules and found their anti-microbial effects and anti-fungal effect against Gram (+) and Malassezia furfur which is known to cause dandruff. Here we present that functional supramolecules-containing cream promotes the biological skin activity by inducing the collagen formation. And treatment of supramolecules-containing hair tonic increased the rate of hair growth of mouse. Taken together, supramolecular cosmetic compounds containing water insoluble phytochemicals and water soluble ${\beta}$-cyclodextrin exhibit the potential ability for hair growth promotion and delaying the aging of skin.

약용식물은 피부와 모발을 보호하는 잠재적 기능을 가지고 있다고 알려져 있다. 수용성 호스트 ${\beta}$-cyclodextrin과 약용식물의 기능성 성분들과의 복합체 형성 시 나타나는 피부와 모발에 미치는 효과에 대하여 조사하였다. 기존의 연구에서 복합체 형성물의 무독성, 그리고 그람양성균과 비듬을 발생시키는 곰팡이에 대한 항균기능성을 확인하였다. 본 연구에서는 약용식물의 기능성 성분을 함유한 크림이 피부의 콜라젠 생성을 유도하여 피부의 생리활성을 증대시킴을 확인하였다. 또한 기능성 성분을 함유한 헤어토닉 처리군에서 육모의 성장이 증진되었음을 생쥐를 이용한 동물실험에서 확인하였다. 본 연구 결과, 비수용성 약용성분을 수용성 ${\beta}$-cyclodextrin에 포접시켜 초분자 복합체 형성을 통해, 육모기능의 향상과 피부노화지연 등 부가적 화장제재로의 개발가능성을 보여주었다.

Keywords

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