Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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A New Megastigmane Glucoside from the Aerial Parts of Erythronium japonicum

  • Lee, Seung-Young (Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University) ;
  • Lee, Il-Kyun (Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University) ;
  • Choi, Sang-Un (Korea Research Institute of Chemical Technology) ;
  • Lee, Kang-Ro (Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University)
  • Received : 2012.06.15
  • Accepted : 2012.07.16
  • Published : 2012.09.30
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Abstract

The purification of the MeOH extract from the aerial parts of Erythronium japonicum using column chromatography furnished a new megastigmane glucoside, erthrojaponiside (1), together with six known megastigmane derivatives (2 - 7). The structure of the new compound (1) was determined through 1D and 2D NMR spectral data analysis and chemical means. The isolated compounds (1 - 7) were tested for cytotoxicity against four human tumor cells in vitro using a Sulforhodamin B (SRB) bioassay.

Keywords

References

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