Mass Spectrometry Letters

Korean Society for Mass Spectrometry (한국질량분석학회)
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Multi-Level Characterization of Protein Glycosylation

  • Hua, Serenus (Cancer Research Institute, Chungnam National University) ;
  • Oh, Myung Jin (Graduate School of Analytical Science and Technology, Chungnam National University) ;
  • An, Hyun Joo (Cancer Research Institute, Chungnam National University)
  • Received : 2013.03.15
  • Accepted : 2013.03.25
  • Published : 2013.03.29
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Abstract

Recent developments in MS-based glycomics and glycoproteomics have rapidly advanced the field and pushed the boundaries of glyco-analysis into new territories. This review will lay out current workflows and strategies for characterization of the glycoproteome, including (in order of increasing complexity and information content) preliminary site mapping, compositional glycan profiling, isomer-specific glycan profiling, glycosite-specific glycopeptide profiling, and finally, glycoproteomic profiling.

Keywords

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