Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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The Study on Pharmacological Activation as Cosmetic Material of Rosa rugosa Thunb. Flowers Extract

해당화꽃 추출물의 화장품소재로서 약리활성에 관한 연구

  • Yu, Hye-Soo (Department of Beauty Design School, Wonkwang University) ;
  • Choi, Ji-Eun (BK21-plus Team, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Woo, Won-Hong (Department of Anatomy, College of Oriental Medicine, Wonkwang University) ;
  • Mun, Yeun-Ja (BK21-plus Team, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 유혜수 (원광대학교 뷰티디자인학과) ;
  • 최지은 (원광대학교 한의학전문대학원 BK21-plus팀) ;
  • 우원홍 (원광대학교 한의과대학 해부학교실) ;
  • 문연자 (원광대학교 한의학전문대학원 BK21-plus팀)
  • Received : 2014.11.20
  • Accepted : 2014.12.15
  • Published : 2014.12.27
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Abstract

Objectives : In this study, we investigated the effect of ethanol extract from Rosa rugosa Thunb. flowers(ERF) on the activities of antioxidant, antiwrinkle and whitening. Methods : We measured antioxidant efficacy of ERF by using 1,1-diphenyl-2-picrylhydrazyl(DPPH) assay. Also we confirmed the inhibitory effect of ERF on collagenase activity and melanin synthesis by using collagenase assay kit and dihydroxiphenylalanine staining, respectively. To evaluate the anti-inflammatory effects of ERF, we examined the inflammatory mediator IL-6. Results : ERF showed highly efficacy in DPPH radical scavenging activity. ERF dose-dependently suppressed collagenase activity. Ultraviolet-induced production of IL-6 decreased by ERF treatment. In B16F10 cell, ERF significantly reduced tyrosinase activity and melanin synthesis. Conclusions : From the above results, it was indicated that ERF could be utilized as anti-aging and whitening cosmetic ingredients.

Keywords

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