Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Effects of Laser Acupuncture Therapy According to the Wavelength at GB34·GB39 on Neuropathic Pain Rat Induced by Tibial and Sural Nerve Transection

양릉천(GB34)·현종(GB39)에 대한 파장대별 레이저침 시술이 동통에 미치는 영향

  • Youn, Daehwan (Department of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Yoo, Pyungsik (Department of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Kim, Wangin (Department of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Kim, Mirea (Department of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Choi, Donghee (Department of Meridian and Acupoint, College of Oriental Medicine, Dongshin University) ;
  • Na, Changsu (Department of Meridian and Acupoint, College of Oriental Medicine, Dongshin University)
  • 윤대환 (동신대학교 한의과대학 경혈학교실) ;
  • 유평식 (동신대학교 한의과대학 경혈학교실) ;
  • 김왕인 (동신대학교 한의과대학 경혈학교실) ;
  • 김미래 (동신대학교 한의과대학 경혈학교실) ;
  • 최동희 (동신대학교 한의과대학 경혈학교실) ;
  • 나창수 (동신대학교 한의과대학 경혈학교실)
  • Received : 2014.12.08
  • Accepted : 2014.12.17
  • Published : 2014.12.27
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Abstract

Objectives : The purpose of this study is to examine the effects of laser acupuncture according to the wavelength(532 nm, 650 nm, 830 nm, 904 nm, and 1064 nm) at the acupoint of GB34 GB39 on neuropathic pain rat induced by tibial and sural nerve transection(TST). Methods : Neuropathic pain in rats was induced by tibial nerve and sural nerve transection. The rats were divided into the intact group, the TST control group, and the laser acupuncture therapy group. The laser acupuncture therapy groups were then divided into subgroups with 532 nm(L532), 650 nm(L650), 830 nm(L830), 904 nm(L904), and 1064 nm(L1064) laser acupuncture therapy. The acupoint of GB34 GB39 was selected, and laser acupuncture therapy was provided on both sides alternatively twice a week in a total of 6 sessions. Results : All the laser acupuncture groups showed a significant decrease in reaction time and force intensity. L532, L904, and L1064 groups showed a significant decrease in Bax, the L532 group showed a significant increase in Bcl-2, L532 and L1064 groups showed a significant decrease in the Bax/Bcl-2 ratio, and L532 and L650 groups showed a significant increase in mGluR5, as compared with the TST control group, among nerve tissue reaction. Conclusions : These results showed that laser acupuncture therapy at each of the wavelengths had some significance on neuropathic pain.

Keywords

References

  1. Raymond DA, Maurice V, Allan HR. Adams and Victor's principles of neurology. Seoul : Jeongdam publisher. 1998 : 121, 134.
  2. C CG. The Gunn Approach to the Treatment of Chronic Pain. Seoul : Kunja publisher. 2006 : 3.
  3. Scott MF, Jane CB, James PR. Bonica's management of pain. Philadelphia : Lippincott Williams & Wilkins. 2001 : 371-85.
  4. Department of Oriental Rehabilitation Medicine. Oriental Rehabilitation Sciences. Seoul : Sewondang publisher. 1995 : 95.
  5. Hwang MD. The Chinese Practical Medicine. Shanghai : Shanghai Science and Technology publishers. 1986 : 554-68.
  6. Gerhard L, Detlef S. Laserneedle Acupuncture. Seoul : Medical Korea. 2007 : 6-18.
  7. Hwang EH, Yang CS, Jang IS. The Spectrum of Laser Instruments for Laser Acupuncture Application. The Journal of Korean Acupuncture & Moxibustion Society. 2009 ; 26(1) : 49-57.
  8. Elseify MY, Mohammed NH, Alsharkawy AA, Elseoudy ME. Laser acupuncture in treatment of childhood bronchial asthma. J Complement Integr Med. 2013 ; 10(1) : 1-5. https://doi.org/10.1515/jcim-2012-0026
  9. Moustafa Y, Kassab AN, El Sharnoubi J, Yehia H. Comparative study in the management of allergic rhinitis in children using LED phototherapy and laser acupuncture. Int J Pediatr Otorhinolaryngol. 2013 ; 77(5) : 658-65. https://doi.org/10.1016/j.ijporl.2013.01.006
  10. Ferreira LA, de Oliveira RG, Guimaraes JP, Carvalho AC, De Paula MV. Laser acupuncture in patients with temporomandibular dysfunction: a randomized controlled trial. Lasers Med Sci. 2013 ; 28(6) : 1549-58. https://doi.org/10.1007/s10103-013-1273-x
  11. Quah-Smith I, Smith C, Crawford JD, Russell J. Laser acupuncture for depression: a randomised double blind controlled trial using low intensity laser intervention. J Affect Disord. 2013 ; 148(2-3) : 179-87. https://doi.org/10.1016/j.jad.2012.11.058
  12. Lin ML, Wu HC, Hsieh YH, Su CT, Shih YS, Lin CW, Wu JH. Evaluation of the effect of laser acupuncture and cupping with ryodoraku and visual analog scale on low back pain. Evid Based Complement Alternat Med. 2012 ; 2012 : 1-7.
  13. Lim JA, Chae WS, Lee SH, SH Jeong, DH Youn, CS Na. Effects of GaAlAs Laser and Acupuncture Therapy at BL40 on Neuropathic Pain in Rats. Kor J Acupuncture. 2011 ; 28(2) : 37-47.
  14. Wei TS, Youn DH, Youn YC, Na CS. Comparative study of acupuncture and invasive Laser acupuncture therapy at SI3, BL40 on the tibial, sural nerve injury and L5 spinal nerve Ligation model in rats. The Kor J Meridian & Acupoint. 2005 ; 22(2) : 9-24.
  15. Kim YS, Lee JH, Lee SH, Na CS, Cho MR. Effects of Electro and Laser Acupuncture Treatment with GB39 and GB34 on Neuropathic Pain in Rats Induced by Tibial and Sural Nerve Ligation. The Acupuncture. 2013 ; 30(3) : 125-34.
  16. The Korean Acupuncture & Moxibustion Society of Compilation Committee. Acupuncture and Moxibustion Medicine. Seoul : Jipmoondang. 2012 : 225, 227-8.
  17. Jan T, Lars H. Laser Therapy. Seoul : Jeongdam publisher. 2006 : 75-107.
  18. Yang KS. Acupuncture & Moxibustion. Beijing : People's medical publishing house. 1988 : 325-6, 328-9.
  19. Lim JK. Acupuncture Therapeutics. Seoul : Jipmoondang. 1983 : 451-2, 454.
  20. Meridians & Acupoints Compilation Committee of Korean Oriental Medical Colleges. Principles of Meridian & Acupoints; A Guidebook for College Students(Volume II). 2009 : 1024-34, 1045-8.
  21. Chae CH, Kim JY, An EN. The Effect of Caloric Restriction and Regular Exercise on Lipid Peroxidation and Bax Bcl-2 mRNA in heart of Aging-induced Rat. The Korean Journal of Exercise Nutrition. 2007 ; 11(3) : 241-7.
  22. Park WS, Kim ES, Shin JW Kim BH, Kim SJ, Kang H et al. Effects of Root of Cibotii Rhizoma on Neuronal Damage of Spinal Cord Contusion Injury in Rats. J Oriental Rehab Med. 2010 ; 20(2) : 1-15.
  23. Gross A, McDonnell JM, Korsmeyer SJ. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev. 1999 ; 13 : 1899-911. https://doi.org/10.1101/gad.13.15.1899
  24. Kim HK, Kim PJ, Baik SW, Kim IS, Chung KS. Molecular Biologic Study on the Changes of Glutamate Receptor (mGluR5) in Rat Hippocampus after Brain Ischemia. Korean J Crit Care Med. 2000 ; 15(2) : 75-81.
  25. Bester H, Matsumoto N, Bessen JM. Further evidence for the involvement of the spinoparabrachial pathway in nociceptive processes: a c-Fos study in the rat. J Comp Neurol. 1997 ; 199 : 383-439.
  26. Robertson GS, Fibiger HC. Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine. Neuroscience. 1992 ; 46 : 315-28. https://doi.org/10.1016/0306-4522(92)90054-6
  27. Bullitt E. Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J Comp Neurol. 1990 ; 296 : 517-30. https://doi.org/10.1002/cne.902960402
  28. Mim JH, Park JM, Moon DY, Kim SY, Jeong C, Kim KH. Fos Expression in the Brain of Neuropathic Pain Rats. Korean J Anesthesiology. 2001 ; 41(2) : 229-37. https://doi.org/10.4097/kjae.2001.41.2.229
  29. Elaine NM. Anatomy and Physiology. Seoul : Gyechuk publisher. 2001 : 487-93.
  30. Kang SY, Ko KS, Ko MH, Ko YW, Ko CW, Kwak JY. The Merck Manual. Seoul : Hanwoori publisher. 2002 : 374.