Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
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Lymphedema Fat Graft: An Ideal Filler for Facial Rejuvenation

  • Nicoli, Fabio (Department of Plastic and Reconstructive Surgery, University of Rome "Tor Vergata") ;
  • Chilgar, Ram M. (Department of Plastic and Reconstructive Surgery, China Medical University Hospital) ;
  • Sapountzis, Stamatis (Department of Plastic and Reconstructive Surgery, China Medical University Hospital) ;
  • Lazzeri, Davide (Plastic Reconstructive and Aesthetic Surgery, Villa Salaria Clinic) ;
  • Yeo, Matthew Sze Wei (Department of Plastic and Reconstructive Surgery, China Medical University Hospital) ;
  • Ciudad, Pedro (Department of Plastic and Reconstructive Surgery, China Medical University Hospital) ;
  • Nicoli, Marzia (Department of Plastic and Reconstructive Surgery, University of Rome "Tor Vergata") ;
  • Lim, Seong Yoon (Department of Plastic and Reconstructive Surgery, China Medical University Hospital) ;
  • Chen, Pei-Yu (Department of Pathology, China Medical University Hospital) ;
  • Constantinides, Joannis (Department of Plastic and Reconstructive Surgery, China Medical University Hospital) ;
  • Chen, Hung-Chi (Department of Plastic and Reconstructive Surgery, China Medical University Hospital)
  • Received : 2014.03.17
  • Accepted : 2014.06.14
  • Published : 2014.09.15
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Abstract

Lymphedema is a chronic disorder characterized by lymph stasis in the subcutaneous tissue. Lymphatic fluid contains several components including hyaluronic acid and has many important properties. Over the past few years, significant research has been performed to identify an ideal tissue to implant as a filler. Because of its unique composition, fat harvested from the lymphedema tissue is an interesting topic for investigation and has significant potential for application as a filler, particularly in facial rejuvenation. Over a 36-month period, we treated and assessed 8 patients with lymphedematous limbs who concurrently underwent facial rejuvenation with lymphedema fat (LF). We conducted a pre- and postoperative satisfaction questionnaire survey and a histological assessment of the harvested LF fat. The overall mean general appearance score at an average of 6 months after the procedure was $7.2{\pm}0.5$, demonstrating great improvement. Patients reported significant improvement in their skin texture with a reading of $8.5{\pm}0.7$ and an improvement in their self-esteem. This study demonstrates that LF as an ideal autologous injectable filler is clinically applicable and easily available in patients with lymphedema. We recommend the further study and clinical use of this tissue as it exhibits important properties and qualities for future applications and research.

Keywords

References

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