DOI QR코드

DOI QR Code

Biofilm formation on denture base resin including ZnO, CaO, and TiO2 nanoparticles

  • Anwander, Melissa (Department of Prosthetic Dentistry, Regensburg University Medical Center) ;
  • Rosentritt, Martin (Department of Prosthetic Dentistry, Regensburg University Medical Center) ;
  • Schneider-Feyrer, Sibylle (Department of Prosthetic Dentistry, Regensburg University Medical Center) ;
  • Hahnel, Sebastian (Department of Prosthetic Dentistry, Regensburg University Medical Center)
  • 투고 : 2017.02.22
  • 심사 : 2017.07.04
  • 발행 : 2017.12.29

초록

PURPOSE. This laboratory study aimed to investigate the effect of doping an acrylic denture base resin material with nanoparticles of ZnO, CaO, and $TiO_2$ on biofilm formation. MATERIALS AND METHODS. Standardized specimens of a commercially available cold-curing acrylic denture base resin material were doped with 0.1, 0.2, 0.4, or 0.8 wt% commercially available ZnO, CaO, and $TiO_2$ nanopowder. Energy dispersive X-ray spectroscopy (EDX) was used to identify the availability of the nanoparticles on the surface of the modified specimens. Surface roughness was determined by employing a profilometric approach; biofilm formation was simulated using a monospecies Candida albicans biofilm model and a multispecies biofilm model including C. albicans, Actinomyces naeslundii, and Streptococcus gordonii. Relative viable biomass was determined after 20 hours and 44 hours using a MTT-based approach. RESULTS. No statistically significant disparities were identified among the various materials regarding surface roughness and relative viable biomass. CONCLUSION. The results indicate that doping denture base resin materials with commercially available ZnO, CaO, or $TiO_2$ nanopowders do not inhibit biofilm formation on their surface. Further studies might address the impact of varying particle sizes as well as increasing the fraction of nanoparticles mixed into the acrylic resin matrix.

키워드

참고문헌

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피인용 문헌

  1. Mechanical and Physicochemical Properties of Newly Formed ZnO-PMMA Nanocomposites for Denture Bases vol.8, pp.5, 2018, https://doi.org/10.3390/nano8050305
  2. Zinc Oxide Nanoparticles Cytotoxicity and Release from Newly Formed PMMA-ZnO Nanocomposites Designed for Denture Bases vol.9, pp.9, 2019, https://doi.org/10.3390/nano9091318
  3. The effect of acidic treatment of carbon fiber on denture mechanical properties vol.1879, pp.3, 2021, https://doi.org/10.1088/1742-6596/1879/3/032082
  4. Nanoparticles in Dentistry: A Comprehensive Review vol.14, pp.8, 2017, https://doi.org/10.3390/ph14080752
  5. Nanoparticle-modified PMMA to prevent denture stomatitis: a systematic review vol.204, pp.1, 2017, https://doi.org/10.1007/s00203-021-02653-4