The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Effects of SM-2015 on Blood Alcohol Clearance and Hangover

SM-2015의 혈중 알코올 분해 및 숙취 개선 효과

  • Shin, Seon-mi (Dept. of Internal Medicine, College of Korean Medicine, Se-Myung University) ;
  • Park, Sun-young (Dept. of Physiology, College of Korean Medicine, Se-Myung University) ;
  • Kim, Tae-yeon (Dept. of Preventive Medicine, College of Korean Medicine, Se-Myung University)
  • 신선미 (세명대학교 한의과대학 내과학교실) ;
  • 박선영 (세명대학교 한의과대학 생리학교실) ;
  • 김태연 (세명대학교 한의과대학 예방의학교실)
  • Received : 2017.02.02
  • Accepted : 2017.02.02
  • Published : 2017.03.30
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Abstract

Objectives: This study investigated the effect of SM-2015 on blood alcohol clearance and hangover. We undertook this study to test whether SM-2015 is effective in decreasing blood alcohol concentration and preventing the symptoms of alcohol-induced hangover. Methods: Twenty healthy volunteers participated in this randomized crossover study. All participants were classified between an SM-2015 intake group (test group) and a non-intake group (control group). The primary outcome measure was the difference in blood alcohol concentration and hangover severity scores between the test and control groups. The secondary outcome measure was the difference in a liver function test (LFT) between the test and control groups. Results: After alcohol exposure, the sensitivity scores of blood alcohol concentration and hangover symptoms (sleepiness, dizziness, nausea, weakness, stomach pain, diarrhea, and concentration disorder) were significantly decreased in the SM-2015 intake group compared with the non-intake group. There were no differences in the LFT results between the SM-2015 intake group and the non-intake group. Conclusions: SM-2015 is effective in decreasing blood alcohol concentration and preventing the symptoms of alcohol-induced hangover. Larger studies are required to confirm these findings.

Keywords

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