DOI QR코드

DOI QR Code

Ileal epithelioid leiomyosarcoma with omental and peritoneal seeding

그물막과 복막파종을 동반한 회장의 상피양 평활근육종

  • Kim, Chung-Hyoun (Department of Internal Medicine, Dongkang Medical Center) ;
  • Kim, Sun-Young (Department of Pathology, Dongkang Medical Center) ;
  • Jung, Chang-Kil (Department of Internal Medicine, Dongkang Medical Center) ;
  • Choi, Jung-Pil (Department of General Surgery, Dongkang Medical Center) ;
  • Seo, Keum-Soo (Department of Radiology, Dongkang Medical Center) ;
  • Lee, Jun-Ho (Department of Internal Medicine, Dongkang Medical Center) ;
  • Choi, Jae-Hyung (Department of Internal Medicine, Dongkang Medical Center)
  • Received : 2016.11.10
  • Accepted : 2017.05.18
  • Published : 2017.06.30

Abstract

Leiomyosarcoma (LMS) of the small intestine is a rare tumor, accounting for about 1% of all malignant mesenchymal lesions in the gastrointestinal tract. Since small bowel tumors are initially asymptomatic and nonspecific, delayed diagnosis and treatment are common. We found that a 44-year-old male patient who came in for lower abdominal pain had partial obstruction in the small bowel. Multiple ascites and ileal tumors involving peritoneal seeding were observed from his abdominal computed tomography. He was diagnosed as epithelioid LMS involving peritoneal transition after surgical resection, and the outpatient department has planned for a conservative therapy with observation. To the best of our knowledge, ileal epithelioid LMS accompanying a huge omental mass, with a size of 18 cm in dimension, and peritoneal seeding has not yet been reported in Korea. We report this rare case with literature review.

Keywords

References

  1. The Korea central cancer registry, national cancer center. Annual report of cancer statistics in Korea in 2009. Seoul: Ministry of health and welfare; 2011.
  2. Bilimoria KY, Bentrem DJ, Wayne JD, Ko CY, Bennett CL, Talamonti MS. Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 years. Ann Surg 2009;249:63-71. https://doi.org/10.1097/SLA.0b013e31818e4641
  3. Agaimy A, Wunsch PH. True smooth muscle neoplasms of the gastrointestinal tract: morphological spectrum and classification in a series of 85 cases from a single institute. Langenbecks Arch Surg 2007;392:75-81. https://doi.org/10.1007/s00423-006-0092-y
  4. Evans HL. Smooth muscle tumors of the gastrointestinal tract. A study of 56 cases followed for a minimum of 10 years. Cancer 1985;56:2242-50. https://doi.org/10.1002/1097-0142(19851101)56:9<2242::AID-CNCR2820560918>3.0.CO;2-5
  5. O’Riordan BG, Vilor M, Herrera L. Small bowel tumors: an overview. Dig Dis 1996;14:245-57. https://doi.org/10.1159/000171556
  6. Conlon KC, Casper ES, Brennan MF. Primary gastrointestinal sarcomas: analysis of prognostic variables. Ann Surg Oncol 1995;2:26-31. https://doi.org/10.1007/BF02303698
  7. Akwari OE, Dozois RR, Weiland LH, Beahrs OH. Leiomyosarcoma of the small and large bowel. Cancer 1978;42:1375-84. https://doi.org/10.1002/1097-0142(197809)42:3<1375::AID-CNCR2820420348>3.0.CO;2-4
  8. Cobrin GM, Pittman RH, Lewis BS. Increased diagnostic yield of small bowel tumors with capsule endoscopy. Cancer 2006;107:22-7. https://doi.org/10.1002/cncr.21975
  9. Schwartz GD, Barkin JS. Small-bowel tumors detected by wireless capsule endoscopy. Dig Dis Sci 2007;52:1026-30. https://doi.org/10.1007/s10620-006-9483-8
  10. Megibow AJ, Balthazar EJ, Hulnick DH, Naidich DP, Bosniak MA. CT evaluation of gastrointestinal leiomyomas and leiomyosarcomas. AJR Am J Roentgenol 1985;144:727-31. https://doi.org/10.2214/ajr.144.4.727
  11. Ohnishi T, Yoshioka H, Ishida O. MR imaging of gastrointestinal leiomyosarcoma. Radiat Med 1991;9:114-7.
  12. Masselli G, Gualdi G. Evaluation of small bowel tumors: MR enteroclysis. Abdom Imaging 2010;35:23-30. https://doi.org/10.1007/s00261-008-9490-7
  13. Triester SL, Leighton JA, Leontiadis GI, Fleischer DE, Hara AK, Heigh RI, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol 2005;100:2407-18. https://doi.org/10.1111/j.1572-0241.2005.00274.x
  14. Kameda N, Higuchi K, Shiba M, Machida H, Okazaki H, Yamagami H, et al. A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding. J Gastroenterol 2008;43:434-40. https://doi.org/10.1007/s00535-008-2182-9
  15. Katz SC, DeMatteo RP. Gastrointestinal stromal tumors and leiomyosarcomas. J Surg Oncol 2008;97:350-9. https://doi.org/10.1002/jso.20970
  16. Blanchard DK, Budde JM, Hatch GF 3rd, Wertheimer-Hatch L, Hatch KF, Davis GB, Foster RS Jr, Skandalakis JE. Tumors of the small intestine. World J Surg 2000;24:421-9. https://doi.org/10.1007/s002689910067
  17. Skandalakis JE, Gray SW, Skandalakis LJ. Metastasis of malignant smooth muscle tumors of the gastrointestinal tract: pattern and process. J Med Assoc Ga 1991;80:701-9.
  18. Lindberg RD, Martin RG, Romsdahl MM, Barkley HT Jr. Conservative surgery and postoperative radiotherapy in 300 adults with soft-tissue sarcomas. Cancer 1981;47:2391-7. https://doi.org/10.1002/1097-0142(19810515)47:10<2391::AID-CNCR2820471012>3.0.CO;2-B
  19. Fernandez-Trigo V, Sugarbaker PH. Sarcomas involving the abdominal and pelvic cavity. Tumori 1993;79:77-91. https://doi.org/10.1177/030089169307900201
  20. Licht JD, Weissmann LB, Antman K. Gastrointestinal sarcomas. Semin Oncol 1988;15:181-8.