한국식품저장유통학회지 (Food Science and Preservation)

  • 제24권5호
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  • Pages.666-672
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  • 2017
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  • 3022-5477(pISSN)
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  • 3022-5485(eISSN)
한국식품저장유통학회 (The Korean Society of Food Preservation)
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장기간의 지구성 운동과 단삼식초 섭취가 고지방식 유도 비만 흰 쥐의 신체구성과 인슐린 저항성에 미치는 영향

Effects of long-term endurance exercise and Salvia miltiorrhiza vinegar on body composition and insulin resistance in high fat diet-induced obese rats

  • 투고 : 2017.06.01
  • 심사 : 2017.07.28
  • 발행 : 2017.08.30
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초록

본 연구는 단삼식초 및 지구성 운동트레이닝이 고지방식 유도 비만 흰쥐의 신체구성 및 혈중 항목들의 농도 변화에 미치는 영향을 비교분석함으로서 대사성 증후군의 개선에 도움을 줄 수 있는 효과적인 방법을 모색하고자 실시되었다. 10주령 수컷 Wistar 흰쥐 40마리를 대상으로 8주간 고지방식 처치로 비만을 유도한 후 좌업군, 운동군, 단삼식초섭취군, 운동군+단삼식초섭취 복합처치군 등으로 무선, 배정하여 총 8주간 운동 및 식이처치를 실시하였으며, 체중 및 신체구성, 식이섭취량, 경구당 부하검사 및 혈중 콜레스테롤 농도 등을 측정하였다. 8주간의 단삼식초섭취는 지구성 운동과 병행할 경우 체중감소 및 인슐린 저항성의 개선효과를 확인할 수 있었다. 그러나 단삼식초섭취만 처치할 경우 오히려 체지방량을 증가시키고 제지방량은 감소시켰으며, 인슐린 저항성을 현저하게 개선시키지 않는 것으로 나타났다. 또한 지구성 운동과의 병행 시도의 경우에도 운동효과를 배제한 부가적인 효과가 나타나지 않았으며, 혈중 지질에 있어서는 운동의 효과마저 둔화시키는 것으로 나타났다. 따라서 단삼식초섭취에 따른 항고혈당, 항비만 효과는 확인될 수 없었으며, 추후 분자생물학적 분석에 의한 기전과 관련된 원인분석을 통해서 보다 명확한 결과를 제시할 수 있을 것으로 생각된다.

The purpose of this study was to examine the effects of long-term endurance exercise and salvia miltiorrhiza vinegar on body composition and insulin resistance of high-fat diet (30% carbohydrate, 50% fat and 20% protein) induced obese rats. After 8 weeks of high fat diet (50% of total calories), rats were divided into 4 groups (sedentary group, n=10; exercise group, n=10; Salvia miltiorrhiza vinegar group, n=10; exercise+Salvia miltiorrhiza vinegar group, n=10) for 8 weeks. Body weight, body composition, diet intake volume, oral glucose tolerance test, plasma total cholesterol were measured. The results showed that Salvia miltiorrhiza vinegar plus endurance exercise training for 8 weeks significantly improved body weight control, visceral fat weight, and insulin resistance. However, only Salvia miltiorrhiza vinegar treatment did not significantly improve body composition and insulin resistance. In addition, there was no additive by the combination of Salvia miltiorrhiza vinegar and endurance exercise in insulin, body fat, and total cholesterol. The reduction of body fat, glucose, insulin and cholesterol by combination was resulted from the exercise. These results suggest that Salvia miltiorrhiza vinegar has slight effect on anti-hyperglycemia and anti-obesity.

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피인용 문헌

  1. Effects of Aerobic Exercise Training and Natural Fermented Vinegar on Body Composition and Cardiopulmonary Function in Middle Aged Women vol.36, pp.3, 2018, https://doi.org/10.5763/kjsm.2018.36.3.126