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Anti-Obesity Effects of Mixture of Cheese, Fermented Red Ginseng and Rubus coreanus Miquel

홍삼·복분자 혼합 발효물을 첨가한 치즈의 항비만 효과

  • Lee, Da young (Dept. of Food & Biotechnology, Woosuk University) ;
  • Kim, Nam Seok (Dept. of Food & Biotechnology, Woosuk University) ;
  • Kim, Ha Rim (Dept. of Food & Biotechnology, Woosuk University) ;
  • Kim, Min Sun (Dept. of Food & Biotechnology, Woosuk University) ;
  • Lee, Chang Hyun (Dept. of Korean Medicine, Woosuk University) ;
  • Oh, Mi Jin (Korea Food Research Institute) ;
  • Oh, Chan Ho (Dept. of Food & Biotechnology, Woosuk University) ;
  • Kim, Jong Suk (Dept. of Rehabilitation Studies, Woosuk University) ;
  • Kim, Myung Soon (Dept. of Alternative Medicine, Woosuk University) ;
  • Kwon, Jin (Dept. of Prosthetics and Orthotics, Korea National College of Welfare)
  • 이다영 (우석대학교 식품생명공학과) ;
  • 김남석 (우석대학교 식품생명공학과) ;
  • 김하림 (우석대학교 식품생명공학과) ;
  • 김민선 (우석대학교 식품생명공학과) ;
  • 이창현 (우석대학교 한의예과) ;
  • 오미진 (한국식품연구원) ;
  • 오찬호 (우석대학교 식품생명공학과) ;
  • 김종석 (우석대학교 재활학과) ;
  • 김명순 (우석대학교 대체의학과) ;
  • 권진 (한국복지대학 의료보장구과)
  • Received : 2017.10.02
  • Accepted : 2018.02.06
  • Published : 2018.04.30

Abstract

This study was investigating the anti-obesity effects of diets with a mixture of cheese, red ginseng and fermented mature fruit of Rubus coreanus Miquel. We fed the experimental diets (SC5, SC10) supplemented with 5% or 10% cheese containing of fermented mixture, then orally administered the extract of fermented mixture (RB100, RB300) at a concentration of 100 or 300 mg/kg body weight to SD rats with high fat diet (HFD). The results were as follows: Sample cheese groups decreased visceral fat mass and adipocyte size of stomach compared to that of HFD group. Additionally, lipid droplets of liver in sample cheese groups were smaller than that in HFD group. The serum triglyceride (TG), total cholesterol (tChol), glucose, leptin, and insulin levels in sample cheese group were lower than that in HFD group. But, the serum adiponectin and HDL-cholesterol (cHDL) levels were higher than that in HFD group. These results suggest that fermentation of red ginseng and Rubus coreanus mixed with cheese might be helpful in preventing obesity in high fat diet-fed rats.

Keywords

References

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