Journal of Ginseng Research

The Korean Society of Ginseng (고려인삼학회)
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Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL-/- mice

  • Saba, Evelyn (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University) ;
  • Kim, Seung-Hyung (Institute of Traditional Medicine & Bioscience, Daejeon University) ;
  • Kim, Sung-Dae (Research Center, Dongnam Institute of Radiological and Medical Sciences) ;
  • Park, Sang-Joon (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University) ;
  • Kwak, Dongmi (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University) ;
  • Oh, Jun-Hwan (R&D Headquarters, Korean Ginseng Corporation) ;
  • Park, Chae-Kyu (R&D Headquarters, Korean Ginseng Corporation) ;
  • Rhee, Man Hee (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University)
  • Received : 2017.03.03
  • Accepted : 2017.04.10
  • Published : 2018.07.15
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Abstract

In this study, we precisely showed how the Rg3-enriched red ginseng extract (Rg3-RGE) lowers glucose, triglyceride, and low-density lipoprotein (LDL) levels in $LDL^{-/-}$ mice. Aspartate aminotransferase/serum glutamic-oxaloacetic transaminase), alanine aminotransferase /serum glutamate-pyruvate transaminase, and steatohepatitis were found to be reduced, and atheroma formation was inhibited by Rg3-enriched red ginseng extract.

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References

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