대한약침학회지 (Journal of Pharmacopuncture)

  • 제21권3호
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  • Pages.168-176
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  • 2018
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  • 2093-6966(pISSN)
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  • 2234-6856(eISSN)
대한약침학회 (KOREAN PHARMACOPUNCTURE INSTITUTE)
권호 표지
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Ethanol and Methanol Concentration in Commonly Used Brands of Ma-al-shaeer in Iran: Estimation of Dietary Intakes and Risk Assessment

  • Shirani, Kobra (Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Bostan, Hassan Badie (Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Baroti, Ashkan (Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Hassanzadeh, Mohammad (Deparment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Khashyarmanesh, Zahra (Deparment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Haghighi, Hamideh Moalemzadeh (Deparment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Karimi, Gholamreza (Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences)
  • 투고 : 2018.01.09
  • 심사 : 2018.08.02
  • 발행 : 2018.09.30
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초록

Objectives: Ma-al-shaeer is a popular beverage in Islamic countries. The aim of this study was to determine the concentrations of methanol and ethanol in most consumed brands of Ma-al-shaeer in Iran. Methods: Eighty-one Ma-al-shaeer samples which commonly used in Iran were provided. Methanol and ethanol contents were determined by gas chromatography with flame ionization detector. Results: The mean methanol concentrations in Iranian and foreign brands was $129.84{\pm}205.38mg/L$ and $110.157{\pm}135.98mg/L$, respectively. Although mean ethanol contents of Iranian brands was $1.2{\pm}2.41mg/L$, ethanol level in foreign ones was lower than LOQ. Conclusion: Since the most Ma-al-shaeer brands had methanol pollution at different levels establishment of a definitive relationship between the methanol content and toxicological effects seem to be vital. EDI of methanol for Iranian people through consumption of Maal-shaeer was determined 0.023mg/kg bw/day.

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