The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Effects of the Korean Medicinal Herbs for Treatment of Benign Prostatic Hyperplasia Induced in Rat Models: A Review

양성 전립선 비대증 유발 쥐에 단미 한약재가 미치는 영향에 관한 연구 분석

  • Bae, In-suk (Dept. of Korean Internal Medicine, Dong-Guk University Bundang Korean Medicinal Hospital) ;
  • Jung, Seung-hyun (Dept. of Korean Internal Medicine, Dong-Guk University Bundang Korean Medicinal Hospital)
  • 배인숙 (동국대학교 분당한방병원 한방내과) ;
  • 정승현 (동국대학교 분당한방병원 한방내과)
  • 투고 : 2018.09.03
  • 심사 : 2018.09.29
  • 발행 : 2018.09.30
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초록

Objectives: This study is to review the effect of Korean medicinal herbs on treatment of benign prostatic hyperplasia induced in rat models, as reported in domestic and foreign journals. Methods: Six electronic databases (EMBASE, PubMed, Oasis, RISS, CENTRAL, and Koreankt) were searched with terms including benign prostatic hyperplasia to identify study reports on treatment of benign prostatic hyperplasia impairment with Korean medicinal herbs. After selecting several studies, the analysis focused on items reflected in the diagnosis of benign prostatic hyperplasia, such as prostate weight, thickness of the prostate epithelium, and prostate specific antigen. Results: Six studies were reviewed. Testosterone propionate was used as a benign prostatic hyperplasia induction material in all the included studies. Cinnamomum verum (CV), Cynanchum wilfordii (CW), Ponciri fructus (PF), Quisqualis indica (QI), Acorus gramineus (AG), and Melandrium firmum (MF) had reduced prostate weight statistically significantly. The QI gave a better response than finasteride in terms of reducing epithelium thickness, and the response was statistically significant. The prostate specific antigen level was lower in the group treated with CV than in the control group. Conclusions: CV, CW, PF, QI, AG, and MF had distinct therapeutic effects. However it is difficult to determine which of these is better by comparing them numerically because the observation items evaluated in a rat model of benign prostatic hyperplasia.

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참고문헌

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피인용 문헌

  1. 전립선비대증 변증도구의 신뢰도 평가 및 IPSS, 요속과의 상관관계에 대한 탐색적 연구 vol.41, pp.6, 2018, https://doi.org/10.22246/jikm.2020.41.6.1052