미생물학회지 (Korean Journal of Microbiology)

  • 제55권2호
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  • Pages.160-163
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  • 2019
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  • 0440-2413(pISSN)
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  • 2383-9902(eISSN)
한국미생물학회 (The Microbiological Society of Korea)
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건강한 한국인 분변으로부터 분리된 Senegalimassilia sp. KGMB 04484 균주의 유전체 염기서열 초안

Draft genome sequence of Senegalimassilia sp. KGMB 04484 isolated from healthy Korean human feces

  • 한국일 (한국생명공학연구원 생물자원센터) ;
  • 강세원 (한국생명공학연구원 생물자원센터) ;
  • 김지선 (한국생명공학연구원 생물자원센터) ;
  • 이근철 (한국생명공학연구원 생물자원센터) ;
  • 엄미경 (한국생명공학연구원 생물자원센터) ;
  • 서민국 (한국생명공학연구원 생물자원센터) ;
  • 김한솔 (한국생명공학연구원 생물자원센터) ;
  • 박승환 (한국생명공학연구원 생물자원센터) ;
  • 이주혁 (한국생명공학연구원 생물자원센터) ;
  • 박잠언 (한국생명공학연구원 생물자원센터) ;
  • 오병섭 (한국생명공학연구원 생물자원센터) ;
  • 유승엽 (한국생명공학연구원 생물자원센터) ;
  • 최승현 (한국생명공학연구원 생물자원센터) ;
  • 이동호 (분당서울대학교병원) ;
  • 윤혁 (분당서울대학교병원) ;
  • 김병용 (천랩) ;
  • 이제희 (천랩) ;
  • 이정숙 (한국생명공학연구원 생물자원센터)
  • Han, Kook-Il (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kang, Se Won (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Ji-Sun (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Keun Chul (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Eom, Mi Kyung (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Suh, Min Kuk (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Han Sol (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Park, Seung-Hwan (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Ju Huck (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Park, Jam-Eon (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Oh, Byeong Seob (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Yu, Seung Yeob (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Choi, Seung-Hyeon (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Dong Ho (Seoul National University Bundang Hospital) ;
  • Yoon, Hyuk (Seoul National University Bundang Hospital) ;
  • Kim, Byung-Yong (ChunLab, Inc.) ;
  • Lee, Je Hee (ChunLab, Inc.) ;
  • Lee, Jung-Sook (Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology)
  • 투고 : 2019.02.14
  • 심사 : 2019.03.20
  • 발행 : 2019.06.30
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초록

본 연구에서는 건강한 한국인 분변으로부터 Senegalimassilia sp. KGMB 04484 균주를 분리하였으며 PacBio Sequel 플랫폼을 이용하여 유전체서열을 분석하였다. 유전체는 G+C 구성비율이 61.18%이며, 2,300개의 유전자와 2,139개의 단백질 코딩 유전자, 21개의 rRNA 및 51개 tRNA로 구성되었으며, 염색체의 크기는 2,748,041 bp였다. 유전체의 주요 특징은 가수분해효소와 지방산생합성 및 대사에 관련된 유전자를 포함한다. 이러한 유전체의 분석은 KGMB 04484 균주가 사람의 건강 및 소화에 관여할 것으로 여겨진다.

Senegalimassilia sp. KGMB 04484 was isolated from fecal samples obtained from a healthy Korean. The whole-genome sequence of Senegalimassilia sp. KGMB 04484 was analyzed using the PacBio Sequel platform. The genome comprises a 2,748,041 bp chromosome with a G+C content of 61.18%, 2,300 total genes, 2,139 protein-coding gene, 21 rRNA genes, and 51 tRNA genes. Also, we found that strain KGMB 04484 had some genes for hydrolysis enzyme, fatty acid biosynthesis and metabolism in its genome based on the result of genome analysis. Those genes of KGMB 04484 may be related to regulation of human health and digest.

키워드

MSMHBQ_2019_v55n2_160_f0001.png 이미지

Fig. 1. Graphical circular map of Senegalimassilia sp. KGMB 04484.

Table 1. General features of Senegalimassilia sp. KGMB 04484

MSMHBQ_2019_v55n2_160_t0001.png 이미지

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