Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Application of porcine small intestinal submucosa (Vetrix BioSIS®) for recurrent corneal sequestrum in an American shorthair cat

  • Kim, Youngsam (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Kang, Seonmi (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Nam, Sunhwa (Dana Animal Hospital Eye Center) ;
  • Yun, Seongjin (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Seo, Kangmoon (Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • Received : 2020.06.04
  • Accepted : 2020.09.10
  • Published : 2020.12.30
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Abstract

A 15-year-old, spayed, female American shorthair cat presented with recurrent corneal sequestrum in the right eye. The cat had undergone superficial keratectomy twice for corneal sequestrum treatment 5 and 11 months previously. Two layers of porcine small intestinal submucosa (SIS; Vetrix BioSIS®) were applied to the surgical corneal defect after keratectomy. Thereafter, clinical signs, such as lacrimation, blepharospasm, and corneal ulcer, disappeared 50 days postoperatively. Moreover, the application of SIS with keratectomy prevented recurrence until 651 days after surgery. SIS could be applied as an additional bioscaffold for surgical repair of corneal sequestrum recurring after superficial keratectomy alone in cats.

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References

  1. Maggs DJ, Miller P, Ofri R. Slatter's Fundamentals of Veterinary Ophthalmology. 6th ed. pp. 213-253, Elsevier Health Sciences, St. Louis, 2018.
  2. Gelatt KN. Veterinary Ophthalmology. 4th ed. pp. 1095-1164, Blackwell Publishing, Ames, 2007.
  3. Gelatt KN, Gelatt JP. Veterinary Ophthalmic Surgery. 1st ed. pp. 191-236, Elsevier Saunders, Maryland Height, 2011.
  4. Goulle F. Use of porcine small intestinal submucosa for corneal reconstruction in dogs and cats: 106 cases. J Small Anim Pract 2012;53:34-43. https://doi.org/10.1111/j.1748-5827.2011.01149.x
  5. Cichocki BM, Myrna KE, Moore PA. Modified penetrating keratoplasty with Acell® bioscaffold implant in seven horses with deep full-thickness corneal stromal abscess. Vet Ophthalmol 2017;20:46-52. https://doi.org/10.1111/vop.12349
  6. Barachetti L, Giudice C, Mortellaro CM. Amniotic membrane transplantation for the treatment of feline corneal sequestrum: pilot study. Vet Ophthalmol 2010;13:326-330. https://doi.org/10.1111/j.1463-5224.2010.00821.x
  7. Badylak SF. Small Intestine Submucosa (SIS): a Biomaterial Conducive to Smart Tissue Remodelling. In: Bell E (ed.). Tissue Engineering: Current Perspective. pp. 179-189, Burkhauser, Cambridge, 1993.
  8. Badylak SF. The extracellular matrix as a scaffold for tissue reconstruction. Semin Cell Dev Biol 2002;13:377-383. https://doi.org/10.1016/S1084952102000940
  9. Shi L, Ramsay S, Ermis R, Carson D. In vitro and in vivo studies on matrix metalloproteinases interacting with small intestine submucosa wound matrix. Int Wound J 2012;9:44-53. https://doi.org/10.1111/j.1742-481X.2011.00843.x
  10. Badylak SF, Coffey AC, Lantz GC, Tacker WA, Geddes LA. Comparison of the resistance to infection of intestinal submucosa arterial autografts versus polytetrafluoroethylene arterial prostheses in a dog model. J Vasc Surg 1994;19:465-472. https://doi.org/10.1016/S0741-5214(94)70073-7
  11. Kropp BP, Rippy MK, Badylak SF, Adams MC, Keating MA, Rink RC, Thor KB. Regenerative urinary bladder augmentation using small intestinal submucosa: urodynamic and histopathologic assessment in long-term canine bladder augmentations. J Urol 1996;155:2098-2104. https://doi.org/10.1016/S0022-5347(01)66117-2
  12. Featherstone HJ, Sansom J, Heinrich CL. The use of porcine small intestinal submucosa in ten cases of feline corneal disease. Vet Ophthalmol 2001;4:147-153. https://doi.org/10.1046/j.1463-5224.2001.00192.x
  13. Bussieres M, Krohne SG, Stiles J, Townsend WM. The use of porcine small intestinal submucosa for the repair of full-thickness corneal defects in dogs, cats and horses. Vet Ophthalmol 2004;7:352-359. https://doi.org/10.1111/j.1463-5224.2004.04055.x
  14. Vanore M, Chahory S, Payen G, Clerc B. Surgical repair of deep melting ulcers with porcine small intestinal submucosa (SIS) graft in dogs and cats. Vet Ophthalmol 2007;10:93-99. https://doi.org/10.1111/j.1463-5224.2007.00515.x
  15. Featherstone HJ, Sansom J. Feline corneal sequestra: a review of 64 cases (80 eyes) from 1993 to 2000. Vet Ophthalmol 2004;7:213-227. https://doi.org/10.1111/j.1463-5224.2004.04028.x