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The Relationship Between Symptoms of Oral Mucosal Diseases and Psychological Status

  • Park, Hye Sook (Department of Dental Technology, Shingu College)
  • Received : 2021.02.16
  • Accepted : 2021.03.09
  • Published : 2021.03.30

Abstract

Purpose: The purpose of this study was to assess the relationship between psychological factors and symptoms of oral mucosal diseases by means of the revised version of the Minnesota Multiphasic Personality Inventory (MMPI-2). Methods: Three hundred and eighteen college students in Gyeonggi-do completed the MMPI-2 and a questionnaire related to symptoms of oral mucosal diseases and collected data were analyzed by Student's t-test and one way ANOVA. Results: Subjects who have experienced herpetic stomatitis revealed significantly higher mean values of T-scores than subjects who have not on hypochondriasis (Hs) and hysteria (Hy) clinical scales of the MMPI-2 (p<0.05). In comparison with subjects who have had recurrent aphthous ulceration, subjects who have not had it manifested significantly higher elevations on the schizophrenia (Sc) clinical scale (p<0.05). Subjects who have suffered oral lichen planus (OLP) showed significantly higher mean values of T-scores than subjects who have not on paranoia (Pa) (p<0.05) and hypomania (Ma) (p<0.01) clinical scales. Mean values of T-scores on Ma clinical scale were significantly higher in subjects having experienced glossodynia than in subjects having not experienced (p<0.05). Subjects having felt taste disturbance exhibited significantly higher elevations on Hs (p<0.0001) and Hy (p<0.01) clinical scales compared to subjects having not. Conclusions: Symptoms of oral mucosal diseases such as herpetic stomatitis, taste disturbance, OLP, and glossodynia were found to be related to Hs, Hy, Pa, Ma clinical scales of the MMPI-2. Therefore, comprehensive psychological evaluations of those oral mucosal diseases may be beneficial in a therapeutic approach.

References

  1. Schmidt DD, Zyzanski S, Ellner J, Kumar ML, Arno J. Stress as a precipitating factor in subjects with recurrent herpes labialis. J Fam Pract 1985;20:359-366.
  2. Pedersen A. Psychologic stress and recurrent aphthous ulceration. J Oral Pathol Med 1989;18:119-122. https://doi.org/10.1111/j.1600-0714.1989.tb00747.x
  3. Gallo CB, Mimura MAM, Sugaya NN. Psychological stress and recurrent aphthous stomatitis. Clinics (Sao Paulo) 2009;64:645-648. https://doi.org/10.1590/S1807-59322009000700007
  4. Cerqueira JDM, Moura JR, Arsati F, Lima-Arsati YBO, Bittencourt RA, Freitas VS. Psychological disorders and oral lichen planus: a systematic review. J Investig Clin Dent 2018;9:e12363. https://doi.org/10.1111/jicd.12363
  5. Chaudhary S. Psychosocial stressors in oral lichen planus. Aust Dent J 2004;49:192-195. https://doi.org/10.1111/j.1834-7819.2004.tb00072.x
  6. Katcher AH, Brightman V, Luborsky L, Ship I. Prediction of the incidence of recurrent herpes labialis and systemic illness from psychological measurements. J Dent Res 1973;52:49-58. https://doi.org/10.1177/00220345730520013501
  7. Freire-Garabal M, Varela M, Riveiro P, et al. Effects of nefazodone on the immune system of mice. Eur Neuropsychopharmacol 2000;10:255-264. https://doi.org/10.1016/S0924-977X(00)00080-8
  8. Akpan A, Morgan R. Oral candidiasis. Postgrad Med J 2002;78:455-459. https://doi.org/10.1136/pmj.78.922.455
  9. Guida RA. Candidiasis of the oropharynx and esophagus. Ear Nose Throat J 1988;67:832, 834-836, 838-840.
  10. Trikkas G, Nikolatou O, Samara C, Bazopoulou-Kyrkanidou E, Rabavilas AD, Christodoulou GN. Glossodynia: personality characteristics and psychopathology. Psychother Psychosom 1996;65:163-168. https://doi.org/10.1159/000289070
  11. Gao J, Chen L, Zhou J, Peng J. A case-control study on etiological factors involved in patients with burning mouth syndrome. J Oral Pathol Med 2009;38:24-28. https://doi.org/10.1111/j.1600-0714.2008.00708.x
  12. Osaki T, Ohshima M, Tomita Y, Matsugi N, Nomura Y. Clinical and physiological investigations in patients with taste abnormality. J Oral Pathol Med 1996;25:38-43. https://doi.org/10.1111/j.1600-0714.1996.tb01221.x
  13. Schiffman SS. Taste and smell losses in normal aging and disease. JAMA 1997;278:1357-1362. https://doi.org/10.1001/jama.1997.03550160077042
  14. Bergdahl M, Bergdahl J. Perceived taste disturbance in adults: prevalence and association with oral and psychological factors and medication. Clin Oral Investig 2002;6:145-149. https://doi.org/10.1007/s00784-002-0169-0
  15. Scully C, el-Maaytah M, Porter SR, Greenman J. Breath odor: etiopathogenesis, assessment and management. Eur J Oral Sci 1997;105:287-293. https://doi.org/10.1111/j.1600-0722.1997.tb00242.x
  16. Pryse-Phillips W. An olfactory reference syndrome. Acta Psychiatr Scand 1971;47:484-509. https://doi.org/10.1111/j.1600-0447.1971.tb03705.x
  17. Oho T, Yoshida Y, Shimazaki Y, Yamashita Y, Koga T. Psychological condition of patients complaining of halitosis. J Dent 2001;29:31-33. https://doi.org/10.1016/S0300-5712(00)00057-9
  18. Tabolli S, Bergamo F, Alessandroni L, Di Pietro C, Sampogna F, Abeni D. Quality of life and psychological problems of patients with oral mucosal disease in dermatological practice. Dermatology 2009;218:314-320. https://doi.org/10.1159/000196973
  19. Ship II, Morris AL, Durocher RT, Burket LW. Recurrent aphthous ulcerations and recurrent herpes labialis in a professional school student population: III. Oral examinations. Oral Surg Oral Med Oral Pathol 1960;13:1438-1444. https://doi.org/10.1016/0030-4220(60)90230-9
  20. Graham JR. MMPI-2: assessing personality and psychopathology. 5th ed. New York: Oxford University Press; 2011. pp. 63-221.
  21. Nakagawa M, Mizuma K, Inui T. Changes in taste perception following mental or physical stress. Chem Senses 1996;21:195-200. https://doi.org/10.1093/chemse/21.2.195
  22. Deems DA, Yen DM, Kreshak A, Doty RL. Spontaneous resolution of dysgeusia. Arch Otolaryngol Head Neck Surg 1996;122:961-963. https://doi.org/10.1001/archotol.1996.01890210037009
  23. Aguayo GA, Vaillant MT, Arendt C, Bachim S, Pull CB. Taste preference and psychopathology. Bull Soc Sci Med Grand Duche Luxemb 2012;(2):7-14.
  24. Vallejo MJ, Huerta G, Cerero R, Seoane JM. Anxiety and depression as risk factors for oral lichen planus. Dermatology 2001;203:303-307. https://doi.org/10.1159/000051777
  25. Allen CM, Beck FM, Rossie KM, Kaul TJ. Relation of stress and anxiety to oral lichen planus. Oral Surg Oral Med Oral Pathol 1986;61:44-46. https://doi.org/10.1016/0030-4220(86)90201-X
  26. McCartan BE. Psychological factors associated with oral lichen planus. J Oral Pathol Med 1995;24:273-275. https://doi.org/10.1111/j.1600-0714.1995.tb01181.x
  27. Lundqvist EN, Wahlin YB, Bergdahl M, Bergdahl J. Psychological health in patients with genital and oral erosive lichen planus. J Eur Acad Dermatol Venereol 2006;20:661-666. https://doi.org/10.1111/j.1468-3083.2006.01559.x
  28. Bergdahl J, Ostman PO, Anneroth G, Perris H, Skoglund A. Psychologic aspects of patients with oral lichenoid reactions. Acta Odontol Scand 1995;53:236-241. https://doi.org/10.3109/00016359509005979
  29. Ivanovski K, Nakova M, Warburton G, et al. Psychological profile in oral lichen planus. J Clin Periodontol 2005;32:1034-1040. https://doi.org/10.1111/j.1600-051X.2005.00829.x
  30. Ott G, Ott C. Glossodynia--psychodynamic basis and results of psychopathometric investigations. J Psychosom Res 1992;36:677-686. https://doi.org/10.1016/0022-3999(92)90057-9
  31. Eli I, Kleinhauz M, Baht R, Littner M. Antecedents of burning mouth syndrome (glossodynia)--recent life events vs. psychopathologic aspects. J Dent Res 1994;73:567-572. https://doi.org/10.1177/00220345940730021301
  32. Grushka M, Sessle BJ, Miller R. Pain and personality profiles in burning mouth syndrome. Pain 1987;28:155-167. https://doi.org/10.1016/0304-3959(87)90113-8
  33. Merigo E, Manfredi M, Zanetti MR, Miazza D, Pedrazzi G, Vescovi P. Burning mouth syndrome and personality profiles. Minerva Stomatol 2007;56:159-167.
  34. Ajmal M, Ibrahim L, Mohammed N, Al-Qarni H. Prevalence and psychological stress in recurrent aphthous stomatitis among female dental students in Saudi Arabia. Clujul Med 2018;91:216-221.
  35. Zwiri AM. Anxiety, depression and quality of life among patients with recurrent aphthous ulcers. J Contemp Dent Pract 2015;16:112-117. https://doi.org/10.5005/jp-journals-10024-1646
  36. Huling LB, Baccaglini L, Choquette L, Feinn RS, Lalla RV. Effect of stressful life events on the onset and duration of recurrent aphthous stomatitis. J Oral Pathol Med 2012;41:149-152. https://doi.org/10.1111/j.1600-0714.2011.01102.x
  37. Al-Omiri MK, Karasneh J, Lynch E. Psychological profiles in patients with recurrent aphthous ulcers. Int J Oral Maxillofac Surg 2012;41:384-388. https://doi.org/10.1016/j.ijom.2011.12.024
  38. Polat C, Duzer S, Ayyildiz H, et al. Association between anxiety, depression, and salivary cortisol levels in patients with recurrent aphthous stomatitis. Turk Arch Otorhinolaryngol 2018;56:166-169. https://doi.org/10.5152/tao.2018.3242
  39. Gavic L, Cigic L, Biocina Lukenda D, Gruden V, Gruden Pokupec JS. The role of anxiety, depression, and psychological stress on the clinical status of recurrent aphthous stomatitis and oral lichen planus. J Oral Pathol Med 2014;43:410-417. https://doi.org/10.1111/jop.12148
  40. Dhopte A, Naidu G, Singh-Makkad R, Nagi R, Bagde H, Jain S. Psychometric analysis of stress, anxiety and depression in patients with Recurrent Aphthous Stomatitis-a cross-sectional survey based study. J Clin Exp Dent 2018;10:e1109-e1114.