Korean Journal of Environmental Agriculture (한국환경농학회지)

The Korean Society of Environmental Agriculture (한국환경농학회)
권호 표지
DOI QR코드

DOI QR Code

Persistence and Degradation Pattern of Acequinocyl and Its Metabolite, Hydroxyl-Acequinocyl and Fenpyroximate in Butterburs (Petasites japonicus Max.)

  • Leesun Kim (Residual Chemical Assessment Division, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Geun-Hyoung Choi (Planning and coordination Bureau, Rural Development Administration) ;
  • Hyun Ho Noh (Residual Chemical Assessment Division, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Hee-Dong Lee (Residual Chemical Assessment Division, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Hak-won Lee (Residual Chemical Assessment Division, National Institute of Agricultural Sciences, Rural Development Administration) ;
  • Kee Sung Kyung (Department of Environmental and Biological Chemistry, College of Agriculture, Life and Environment Science, Chungbuk National University) ;
  • Jin-Ho Ro (Technology Service Team, National Institute of Agricultural Sciences, Rural Development Administration)
  • Received : 2023.04.12
  • Accepted : 2023.06.02
  • Published : 2023.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Persistence and degradation patterns of acequinocyl and its metabolite, hydroxyl-acequinocyl (acequinocyl-OH) and fenpyroximate in butterburs (Petasites japonicus Max.) were investigated after pesticide application. Butterburs, one of the minor crops in South Korea, was planted in two plots (plot A for double and plot B for single application) in a greenhouse. Butterburs samples were also planted in a separate plot without pesticide treatment, as the control. A commercial pesticide containing acequinocyl and fenpyroximate was applied to the foliage of butterburs at hourly intervals after dilution. Recoveries of acequinocyl and acequinocyl-OH were 78.6-84.7% and 83.7-95.5%, respectively; the relative standard deviation of the two compounds were less than 5%. The method limit of quantification was 0.01 mg/kg. The total (Ʃ) acequinocyl residues in butterburs reduced by 96.0% at 14 days and 75.9% at 7 days, in plot A and B, respectively, after final pesticide applications. The biological half-life (DT50) of Ʃ acequinocyl and fenpyroximate, calculated using the dissipation rate, was 3.0 days and 4.0 days, respectively. These data were used to set up maximum residue and safe standard levels when the pesticides are applied to control pests during butterbur cultivation. Risk assessment results showed that the maximum % acceptable daily intake was 7.74% for Ʃ acequinocyl and 0.16% for Ʃ fenpyroximate. The theoretical maximum daily intake of Ʃ acequinocyl and fenpyroximate was 26.3% and 35.8%, respectively. In conclusion, the concentrations of Ʃ acequinocyl and fenpyroximate in butterburs pose no significant health risks to Koreans.

Keywords

Acknowledgement

This study was supported by "the RDA Research Associate Fellowship Program of National Institute of Agricultural Sciences" and, "Research Program for Agricultural Science & Technology Development (PJ01224902)" Rural Development Administration, Republic of Korea.

References

  1. OECD (2014) OECD Guidance Document on Defining Minor Uses of Pesticides. https://doi.org/10.1787/9789264221703-en. 
  2. Lee J, Jung MW, Lee J, Lee J, Shin Y, Kim JH (2019) Dissipation of the insecticide cyantraniliprole and its metabolite IN-J9Z38 in proso millet during cultivation. Scientific Reports, 9(1), 11648. https://doi.org/10.1038/s41598-019-48206-0. 
  3. Lamichhane JR, Arendse W, Dachbrodt-Saaydeh S, Kudsk P, Roman JC, van Bijsterveldt-Gels JEM, Wick M, Messean A (2015) Challenges and opportunities for integrated pest management in Europe: A telling example of minor uses. Crop Protection, 74, 42-47. https://doi.org/10.1016/j.cropro.2015.04.005. 
  4. Lee MG (2013) Management and regulation on the minor use of pesticides in Korea and foreign countries. The Korean Journal of Pesticide Science, 17(3), 231-236. https://doi.org/10.7585/kjps.2013.17.3.231. 
  5. Lee JS, Jeong M, Park S, Ryu SM, Lee J, Song Z, Guo Y, Choi JH, Lee D, Jang DS (2019) Chemical constituents of the leaves of butterbur (Petasites japonicus) and their anti-inflammatory effects. Biomolecules, 9(12), 806. https://doi.org/10.3390/biom9120806. 
  6. Matsuura H, Amano M, Kawabata J, Mizutani J (2002) Isolation and measurement of quercetin glucosides in flower buds of Japanese butterbur (Petasites japonicus subsp. gigantea Kitam.). Bioscience, Biotechnology, and Biochemistry, 66(7), 1571-1575. https://doi.org/10.1271/bbb.66.1571. 
  7. Seo HS, Jeong BH, Cho YG (2008) The antioxidant and anticancer effects of butterbur (Petasites japonicus) extracts. Korean Journal of Plant Resources, 21(4), 265-269. 
  8. USDA FAS (2018) Implementation of Positive List System for Maximum Residue Limits. 
  9. Suh E, Koh SH, Lee JH, Shin KI, Cho K (2006) Evaluation of resistance pattern to fenpyroximate and pyridaben in Tetranychus urticae collectedfrom greenhouses and apple orchards using lethal concentration-slope relationship. Experimental & Applied Acarology, 38, 151-165. https://doi.org/10.1007/s10493-006-0009-z. 
  10. Yorulmaz Salman S, Saritas E (2014) Acequinocyl resistance in Tetranychus urticae Koch (Acari: Tetranychidae): inheritance, synergists, cross-resistance and biochemical resistance mechanisms. International Journal of Acarology, 40(6), 428-435. https://doi.org/10.1080/01647954.2014.944932. 
  11. Marcic D (2012) Acaricides in modern management of plant-feeding mites. Journal of Pest Science, 85(4), 395-408. https://doi.org/10.1007/s10340-012-0442-1. 
  12. Park CH, Kim MY, Sok DE, Kim JH, Lee JH, Kim MR (2010) Butterbur (Petasites japonicus Max.) extract improves lipid profiles and antioxidant activities in monosodium ᴸ-glutamate-challenged mice. Journal of Medicinal Food, 13(5), 1216-1223. https://doi.org/10.1089/jmf.2009.1380. 
  13. Malhat F, El-Mesallamy A, Assy M, Madian W, Loutfy NM, Ahmed MT (2013) Residues, half-life times, dissipation, and safety evaluation of the acaricide fenpyroximate applied on grapes. Toxicological & Environmental Chemistry, 95(8), 1309-1317. https://doi.org/10.1080/02772248.2013.877245. 
  14. Caboni P, Sarais G, Melis M, Cabras M, Cabras P (2004) Determination of acequinocyl and hydroxyacequinocyl on fruits and vegetables by HPLC-DAD. Journal of Agricultural and Food Chemistry, 52(22), 6700-6702. https://doi.org/10.1021/jf0487304. 
  15. European Food Safety Authority (EFSA) (2016) Modification of the existing maximum residue level for acequinocyl in gherkins. EFSA Journal, 14(8), e04568. https://doi.org/10.2903/j.efsa.2016.4568. 
  16. Na TW, Rahman MM, Park JH, Yang A, Park KH, Abd El-Aty AM, Shim JH (2012) Residual pattern of acequinocyl and hydroxyacequinocyl in perilla leaf grown under greenhouse conditions using ultra performance liquid chromatography-photo diode array detector with tandem mass confirmation. Journal of the Korean Society for Applied Biological Chemistry, 55, 657-662. https://doi.org/10.1007/s13765-012-2101-x. 
  17. Hwang KW, Bang WS, Jo HW, Moon JK (2015) Dissipation and removal of the etofenprox residue during processing in spring onion. Journal of Agricultural and Food Chemistry, 63(30), 6675-6680. https://doi.org/10.1021/acs.jafc.5b02345. 
  18. Chun OK, Kang HG (2003) Estimation of risks of pesticide exposure, by food intake, to Koreans. Food and Chemical Toxicology, 41(8), 1063-1076. https://doi.org/10.1016/S0278-6915(03)00044-9. 
  19. Korea Health Industry Development Institute (KHIDI) (2016) National food & nutrition statistics I: Based on 2014 Korea national health and nutrition examination survey; 20 September 2020. 
  20. Kim YA, Abd El-Aty AM, Rahman MM, Jeong JH, Shin HC, Wang J, Shin S, Shim JH (2018) Method development, matrix effect, and risk assessment of 49 multiclass pesticides in kiwifruit using liquid chromatography coupled to tandem mass spectrometry. Journal of Chromatography B, 1076, 130-138. https://doi.org/10.1016/j.jchromb.2018.01.015. 
  21. Malhat F, Abdallah O, Anagnostopoulos C, Hussien M, Purnama I, Helmy RMA, Soliman H, El-Hefny D (2022) Residue, dissipation, and dietary intake evaluation of fenpyroximate acaricide in/on guava, orange, and eggplant under open field condition. Frontiers in Nutrition, 9, 939012. https://doi.org/10.3389/fnut.2022.939012. 
  22. Farha W, Abd El-Aty AM, Rahman MM, Shin HC, Shim JH (2016) An overview on common aspects influencing the dissipation pattern of pesticides: A review. Environmental Monitoring Assessment, 188, 693. https://doi.org/10.1007/s10661-016-5709-1. 
  23. Lewis K, Tzilivakis J (2017) Development of a data set of pesticide dissipation rates in/on various plant matrices for the pesticide properties database (PPDB). Data, 2(3), 28. https://doi.org/10.3390/data2030028. 
  24. Dekeyser MA (2005) Acaricide mode of action. Pest Management Science, 61(2), 103-110. https://doi.org/10.1002/ps.994. 
  25. European Food Safety Authority (EFSA) (2013) Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate. EFSA Journal, 11(12), 3493. https://doi.org/10.2903/j.efsa.2013.3493. 
  26. Fenoll J, Ruiz E, Hellin P, Lacasa A, Flores P (2009) Dissipation rates of insecticides and fungicides in peppers grown in greenhouse and under cold storage conditions. Food Chemistry, 113(2), 727-732. https://doi.org/10.1016/j.foodchem.2008.08.007. 
  27. Noh HH, Lee JY, Park HK, Lee JW, Jo SH, Lim JB, Shin HG, Kwon H, Kyung KS (2019) Dissipation, persistence, and risk assessment of fluxapyroxad and penthiopyrad residues in perilla leaf (Perilla frutescens var. japonica Hara). PLoS One, 14(4), e0212209. https://doi.org/10.1371/journal.pone.0212209.