Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
권호 표지
DOI QR코드

DOI QR Code

Skin Barrier Strengthening and Moisturizing Effect of Essence Containing Coptis Japonica Extract

황련 추출물을 함유한 에센스의 피부장벽강화 및 보습 효과

  • Kyung Nam Min (Department of Cosmetics Inventive Design, Anyang University)
  • 민경남 (안양대학교 화장품발명디자인학과)
  • Received : 2023.09.22
  • Accepted : 2023.10.24
  • Published : 2023.10.31
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study is to verify the effect of essence containing Coptis Japonica extract on skin barrier strengthening and moisturizing. The essence containing the Coptis Japonica extract was used by 22 subjects for four weeks, and the amount of percutaneous water loss (g/m2h) and water (A.U.) in the designated upper limit were measured. As a result of measuring percutaneous water loss using a vapometer, it was found to be 11.08±2.55 after 4 weeks of use from 14.82±4.01 before use, and the significance probability decreased significantly by 25.27% to p<0.001. The amount of skin moisture measured by the Corneometer was found to be 46.73±7.45 after use from 31.73±8.09 before use, and the significance probability increased by 47.26% to p<0.001, and the subject's subjective efficacy evaluation through a questionnaire showed that all subjects were 100% satisfied without skin adverse reactions. As a result of this, it has been confirmed that Coptis Japonica essence is effective in strengthening skin barriers and moisturizing, which is expected to be a cornerstone for the development of cosmetics using various activities of Coptis Japonica extract in the future.

본 연구는 황련 추출물을 함유한 에센스가 피부 장벽 강화와 보습에 미치는 영향을 검증하는데 목적을 두고 있다. 황련 추출물을 함유한 에센스를 22명의 피험자에게 4주간 사용하게 한 후 지정한 상박 부위의 경피 수분 손실량(g/m2h)과 수분량(A.U.)을 측정하였다. Vapometer를 이용하여 경피 수분 손실량을 측정한 결과 사용 전 14.82±4.01에서 4주 사용 후 11.08±2.55로 나타났고 유의 확률은 p<0.001로 25.27% 유의하게 감소하였다. Corneometer로 측정한 피부 수분량은 사용 전 31.73±8.09에서 사용 후 46.73±7.45로 나타났고 유의 확률은 p<0.001로 47.26% 증가하였으며 설문을 통한 효능평가에서 피부 이상 반응 없이 두 항목 모두 100% 개선된 것으로 나타났다. 이와 같은 결과로 황련 에센스는 피부 장벽 강화와 보습에 효과적인 것으로 확인되었고 이는 향후 황련 추출물의 다양한 활성을 이용한 화장품 개발에 초석이 될 것으로 기대된다.

Keywords

References

  1. BA Gilchrest, "Skin aging and photoaging an overview", Journal of the American Academy of Dermatology, Vol.21, No.3 pp. 609-654, (1989).  https://doi.org/10.1016/S0190-9622(89)70227-9
  2. S. M. Kim, I. Y. Song, M. K. Yang, J. S. Jung. Skin Science. pp.11-25, Hyunmoonsa, (2006). 
  3. D. Shier, J. Butler, R. Lewis. Hole's Essentials of Human Anatomy & Physiology. pp. 122-132, Mc Graw Hill, (2012). 
  4. M. N. Cha. Comparison of Skin Hydration Effect of Sodium hyaluronate and Liposome hyaluronate. pp.29-30, Konkuk University Master's Thesis, (2010). 
  5. K. C. Madison, "Barrier function of the skin: "La raiꠓson d'etre" of the epidermis", Journal of Investigative Dermatology, Vol.121, No.2 pp. 231-241, (2003).  https://doi.org/10.1046/j.1523-1747.2003.12359.x
  6. S. H. Park, K. K. Lee, K. S. Lee, H. J. Park, B. H. Lee "A Effect of Moisturizing Cream containing Ceramide from Evening Primrose Oil on the Moisturization and Transepidermal Water Loss in Human Skin", Journal of Oil & Applied Science, Vol.35, No.4 pp. 1243-1249, (2018). 
  7. M. Hara, T. Ma, A. S. Verkman, "Selectively reduced glycerol in skin of aquaporin-3 deficient mice may account for impaired skin hydration, elasticity and barrier recovery", Journal of Biological Chemistry, Vol.277, No.48 pp. 46616-46621, (2002).  https://doi.org/10.1074/jbc.M209003200
  8. J. J. Li, Y. H. Liu, J. B. Luo, P. X. Liu, C. H. Zhang, "Excellent lubricating behavior of Brasenia schreberi mucilage", Journal of the American Chemical Society, Vol.28, No.20 pp. 7797-7802, (2012).  https://doi.org/10.1021/la300957v
  9. S. H. Park, K. K, Lee, K. S. Lee, B. H. Lee "The Effect of Surfactant on the Moisturization and Transepidermal Water Loss in Human skin" Journal of oil & applied science, Vol.3, No.2 pp. 560-567, (2018). 
  10. H. J. Jang. A Study on the Influence of Moisturizing Raw Materials on the Cytotoxicity and Skin Moisture. pp.6-7, Konkuk University Master's Thesis, (2005). 
  11. Y. J. Ji, J. W. Lee, I. S. Lee, "Antimicrobial effect of medicinal plants against methicllin-resistant Staphylococcus aureus(MRSA)", Journal of Life Science, Vol.17, No.3 pp. 412-419, (2007).  https://doi.org/10.5352/JLS.2007.17.3.412
  12. B. S. Kim, "Antifungal activity of Zanthaxylum schinifolium against Fusarium graminearum, a barley powdery mildew fungus", Journal of Life Science, Vol.18, No.7 pp. 974-979, (2008).  https://doi.org/10.5352/JLS.2008.18.7.974
  13. E. H. Kim, Y. L. Moon, Y. A. Jang, "Skin Moisturizin Properties and Anti-Inflammatory effects ofextracts from Coptis chinensis in HaCaT cells", Journal of the Korean Applied Science and Technology, Vol.38, No.3 pp. 870-882, (2021).  https://doi.org/10.12925/JKOCS.2021.38.3.870
  14. S. H. Park, K. S. Lee, K. K. Lee, B. H. Lee, "The Effect of Surfactant on the Moisturization and Transepidermal Water Loss in Human skin", Journal of Oil & Applied Science, Vol.35, No.2 pp. 560-567, (2018). 
  15. M. H. Kwak, I. Y. Kim, L. H. Myung, J. H. Park, "A Study on the Moisturizing Effect and Preparation of Liquid Crystal Structures Using Sucrose Distearate Emulsifier", Journal of the Korean Oil Chemists Society, Vol.33, No.1 pp. 1-12, (2016).  https://doi.org/10.12925/jkocs.2016.33.1.1
  16. C. S. Ki, H. Y. Shin, J. S. Kim, C. B. Jeong, B. G. Chae, S. H. Han, G. W. Nam, "Tailored Formulation and Evaluation of Water/Oil Type Emulsionfor Sustained Moisturizing Effect", Applied Chemistry, Vol.14, No.2 pp. 45-46, (2010). 
  17. I. Y. Kim, C. K. Zhoh, H. C. Ryoo, "Formation of Provitamin-B Liquid Crystal with Hydrogenated Lecithin and Its Effectiveness of Moisturizing Activity", Journal of oil & applied sciencev, Vol.20, No.2 pp. 101-109, (2003). 
  18. S. H. Park, K. K. Lee, K. S. Lee, H. J. Park, B. H. Lee, "A Effect of Moisturizing Cream containing Ceramide from Evening Primrose Oil on the Moisturization and Transepidermal Water Loss in Human Skin", Journal of Oil & Applied Science, Vol.35, No.4 pp. 1243-1249, (2018). 
  19. I. Y. Kim, C. K. Zhoh, S. R. Han, Y. B. Bang, R. Y. Li, "Anti-oxidative Activity and Moisturizing Effect of Fermented Puer Tea Extract", Journal of the Korean Oil Chemists Society, Vol.30, No.2 pp. 272-279, (2013).  https://doi.org/10.12925/jkocs.2013.30.2.272
  20. W. G. Cho, S. J. Kim, "Formation of Skin Lotions Using Various Vehicles and Skin Hydration Effects for a Skin", Journal of the Korean Oil Chemists Society, Vol.26, No. 2 pp. 124-131, (2009). 
  21. K. N. Min, "Safety Effect of Cosmetics Containing Coptis Japonica Extract on Sensitive Skin", The Korean Society of Applied Science and Technology, Vol.40, No.3 pp. 453-461, (2023).