권호 표지

Mass Spectrometry Letters

한국질량분석학회 (Korean Society for Mass Spectrometry)

  • 계간
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  • 2233-4203(pISSN)
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  • 2093-8950(eISSN)

Aim & Scope

Mass Spectrometry Letters publishes brief letters (maximum length of 4 pages), technical notes, articles, reviews, and tutorials on fundamental research and applications in all areas of mass spectrometry. The manuscripts can be either invited by the editors or submitted directly by authors to the journal editors. Mass Spectrometry Letters topical sections are diverse, covering ion chemistry in a broad sense; gas-phase thermodynamics or kinetics; theory and calculations related with mass spectrometry or ions in vacuum; ion-optics; analytical aspects of mass spectrometry; instrumentations; methodology developments; ionization methods; proteomics and its related research; metabolomics and its related research; bioinformatics; software developments; database development; biological research using mass spectrometry; pharmaceutical research by mass spectrometry; food sciences using mass spectrometry; forensic results using mass spectrometry; environmental mass spectrometry; inorganic mass spectrometry; chromatography-mass spectrometry; tandem mass spectrometry; small molecule research using mass spectrometry; TOF-SIMS, etc. The scope of Mass Spectrometry Letters is not limited to the above-mentioned areas, but includes ever-expanding areas related directly or indirectly to mass spectrometry. Criteria for publication are originality, urgency, and reportable values. Short preliminary or proof-of-concept results, which will be further detailed by the following submission to other journals, are recommended for submission.

http://www.msletters.org KSCI KCI SCOPUS

제14권1호

  1. Jun Sang Yu;So Young Jo;Il-Ho Park;Hye Hyun Yoo 1
    https://doi.org/10.5478/MSL.2023.14.1.1 PDF HTML
    Eutylone, dibutylone, and dimethylone are potential psychotropic designer drugs. The purpose of this study was to investigate the in vitro metabolic pathways of synthetic cathinones with methylenedioxy groups. The three methylenedioxy derivatives were incubated with human liver microsomes. The metabolites were characterized based on liquid chromatography and quadrupole-time-of-flight mass spectrometry. Eutylone, dibutylone, and dimethylone were metabolized to yield three, six, and four metabolites, respectively. Reduction and demethylenation were the major metabolic pathways for all three drugs tested. However, dibutylone and dimethylone showed an additional metabolite generated via N-oxidation. These results provide evidence for the in vivo metabolism of methylenedioxy synthetic cathinones, and could be applied to the analysis of synthetic cathinones and their relevant metabolites in biological samples.
  2. J. Varshini Premakumari;M. Job Gopinath;B. Narmadha 9
    https://doi.org/10.5478/MSL.2023.14.1.9 PDF HTML
    Plants are able to produce a large number of diverse bioactive compounds. Solvent extraction is used for isolation of plant metabolites. The extract yield for plant metabolite extraction strongly depends on the nature of solvent. A review showed the methanol can yield more bioactive compounds. Drying of the sample material is also important for the extraction of plant material. The present study was carried out to analyze the phytocomponents of 5 different latex producing plants. The plants like Calotropis gigantea, Carica papaya, Nerium oleander, Ficus benghalensis and Plumeria alba leaves and latex. The GC-MS analysis of the metabolites revealed phytocomponents. Calotropis gigantea leaves showed 14 compounds and latex produced 5 compounds out of this 4,4,6A,6B,8A,11,11,14B-Octamethyl-1,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-Octadeca-hydro-2 and 2R- Acetoxymethyl-1,3,3-trimethyl-4T-(3-Methyl-2-Buten-1-Yl)-1T-Cyclohexanol compound was present in both latex and leaf extraction. Beta. -carotene compound was present in both latex and leaf of Carica papaya. It was observed that Ficus benghalensis contained 2R-Acetoxymethyl-1,3,3-trimethyl-4T-(3-Methyl-2-Buten-1-Yl)-1T-Cyclohexanol was same in latex and leaf extraction.