권호 표지

Environmental Analysis Health and Toxicology

환경독성보건학회 (The Korean Society of Environmental Health and Toxicology)

  • 계간
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  • 2671-9525(eISSN)

과학기술표준분류

  • 환경 ＞ 환경보건

Aim & Scope

Environmental Analysis Health and Toxicology (EAHT) is an open access, peer-reviewed, online journal that receives manuscripts on the fields of research, policy, and teaching of environmental analysis health and toxicology. The journal is published online and includes original articles, reviews, meeting reports, brief reports, case reports, investigation reports, special topics, editorials, and letters. EAHT is formerly known as Environmental Health and Toxicology (2011-2019) and Korean Journal of Environmental Toxicology (1986-2010) and has a 34 year history of publication in the field of environmental analysis, health and toxicology with peer review process. EAHT is an official international journal of The Korean Society of Environmental Health and Toxicology/Korea Society for Environmental Analysis (KOSEHT) and the Korean Society for Environmental Analysis (KSFEA). It is also supported by the Korean Federation of Science and Technology Societies (KOFST) Grant funded by the Korean Government. EAHT has multidisciplinary areas of environmental analysis, health and toxicology, including chemical and biological analysis of environmental contamination, ecotoxicology and risk assessment, environmental chemistry, human toxicology and risk assessment, environmental epidemiology, and environmental exposure assessment. EAHT considers manuscripts that have not been published previously (except as an abstract), and are not being considered for publication elsewhere. A paper presented at a scientific meeting may be considered if it has not been published in full in a proceedings or similar publication. Any closely related manuscript either published, in press, or under review must be sent via e-mail to the journal office at the time of the submission to EAHT. This will allow for a full and fair evaluation of the independent contribution of the submitted paper. EAHT is indexed/tracked/covered by PubMed, PubMed Central, Scopus, ScienceCentral, KoreaMed, KoMCI, Directory of Open Access Journals, and Google Scholar. Journal abbreviation: Environ Anal Health Toxicol

https://submit.eaht.org/ KSCI

제22권2호통권57호

  1. 김호현;임영욱;양지연;이용진;서일;김창수;신동천 103
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    대기 중 휘발성유기화합물류(VOCs)의 배출원은 매우 다양하며, 특히, 공단에서 배출되는 VOCs 노출로 인한 공단 주변거주지역 주민에게 배출특성 및 물질별 독성에 따라 유해한 건강 영향을 끼칠 가능성이 있다. 또한 일반가정에서의 자체 실내 오염원 또한 휘발성유기화합물류의 노출의 한 원인이다. 본 연구에서는 공단 주변 거주지역 및 동일 행정구역상의 비교지역을 선정하여 공단배출로 인한 실내유입 VOCs 노출 및 자체 실내오염원으로 인한 농도분포 및 기여정도를 조사하였다. 본 연구에서 공단주변 거주지역 및 비교지역의 조사된 실내 평균 농도는 MTBE 2.24, $2.47{\mu}g/m^3$, benzene 9.82, $8.51{\mu}g/m^3$, toluene 103.80, $83.57{\mu}g/m^3$, ethylbenzene 36.45, $15.52{\mu}g/m^3$, xylene 26.27, $1.00{\mu}g/m^34로 비교지역 거주지에 비해 공단지역 주변거주지의 실내공기 중 VOCs 의 농도가 높은 것으로 나타났다. 최종적으로 I/O ratio를 비교한 결과 조사 거주지 모두 자체 실내오염원이 있는 것으로 관찰되었고, 공단지역 주변거주지의 경우 공단의 VOCs 배출로 의해 추가 노출이 되는 것으로 각각 조사되었다.
  2. 최민규;천만영 111
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    This study was performed to measure gaseous Organochlorine Pesticides (OCPs : heptachlor epoxide, ${\alpha}/{\gamma}-chlordane$, trans-nonachlor, endosulfan, ${\gamma}-HCH$ and p, p'-DDE) concentration using PUF high volume sampler from June, 2000 to June, 2002 in the semi-rural atmosphere. Using monitoring data for two years, we tried to investigate the annual cycles of gaseous OCPs. We considered three functions to describe the annual cycle: Gaussian, Lorentzian and sinusoidal functions. These functions accounted for $54{\sim}91%$ of the variability in concentration for each gaseous OCPs, and the sinusoidal function gave the best fits. It was seen that the gaseous OCPs concentration increased during the warmer weather while decreased during colder weather. The variation of the gaseous OCPs concentration was closely similar to the variations of ambient temperature. The annual cycle of endosulfan was strongly higher than in comparison with other gaseous OCPs, while for ${\gamma}-HCH$, the cycle was weakly high and did not show apparent seasonal variation. The position of the annual maximum exists generally late July to early August. The period that showed levels more than a half maximum was from late June to early September.
  3. 이재우;박정준;진영국;정애진;조현서;이정식 119
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    The present study was conducted to find out effect of PFOS on survival, activity, growth and organ structure of the melania snail, Semisulcospira gottschei. Experimental groups were composed of one control condition and four PFOS exposure condition (0.1, 0.5, 1.0 and 5.0 mg/L). After 16 week exposure, survival rate and activity were not significantly influenced at the two lower exposure groups, 0.1 and 0.5 mg/L, but they were significantly reduced in 1.0 and 5.0 mg/L groups. Total weight and meat weight rate (MWR) were reduced in PFOS exposure group in comparison to control group. Also, histological degenerations such as acidification of mucous, necrosis and split of muscular fiber bundle, atrophy of anterior pedal gland were recognized in the foot. Hepatopancreas showed the atrophy and degeneration of the digestive cell, vacuolation of digestive gland and closure of lumen in digestive gland.
  4. 남재작;홍석영;이종식;소규호;이상학 129
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    Polycyclic aromatic hydrocarbons(PAHs) have been analyzed to assess vertical distribution of them with different land uses. The soils were collected from three layers; surface $(0{\sim}5cm)$, intermediate $(6{\sim}10cm)$, and deep $(11{\sim}15cm)$ layer, respectively considering land use; paddy, upland, and mountain in each site. Total 89 samples of soil from 10 sites were analyzed. Overall mean of ${\sum}PAHs$ were 137 (range $8.87{\sim}625{\mu}g\;kg^{-1}$), 203 (range $16.5{\sim}645{\mu}g\;kg^{-1}$), and $83.4{\mu}g\;kg^{-1}$ (range $6.65{\sim}667{\mu}g\;kg^{-1}$) for paddy, upland, and mountain soil, respectively. The dominant PAHs were fluoroanthene/benzo(b)fluoroanthene>pyrene>indeno(1, 2, 3-cd) pyrene in paddy, fluoroanthene/pyrene>benzo(b)fluoroanthene>chrysene in upland, and benzo(b)fluoroanthene>pyrene>chrysene in mountain soil, whereas the profile was quite similar for each other except that indeno(1, 2, 3-cd)pyrene and benzo(ghi)perylene are relatively higher in the paddy soils. Although the concentration gradient by depth was not observed in the paddy and upland soils because perturbation of soil layer by tillage, significant decrease was in the deep layer relative to the surface and intermediate layer. However, the concentration gradient of PAHs by soil depth was clearly shown in mountain soil without experiencing disturbance of tillage.
  5. 석선미;이태구;김영채;문창현;백은주;정이숙;이수환 137
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    The effect of cadmium chloride $(CdCl_2)$ on the expression of E-cadherin was examined in bEnd.3 mouse brain endothelial cells. $CdCl_2$ induced $PGE_2$ release, which were blocked by non-steroidal antinflamatory drugs (NSAIDs) such as indomethacin and NS398 indicating the expression of COX-2 might contribute to $PGE_2$ production. $CdCl_2$ decreased the expression of E-cadherin, but not VE-cadherin at levels of mRNA and protein. Reduced expression level of E-cadherin was restored by NSAIDs, which was reversed by the addition of $PGE_2$. $CdC_2$-induced decrease of E-cadherin level was also recovered by antioxidants including N-acetylcyteine (NAC) and trolox. Together with previous report which showed $CdCl_2$ induced COX-2 expression in a cellular oxidative stress dependent manner, these data suggest that $CdCl_2$ decreases E-cadherin expression through induction of cellular oxidative stress and in turn COX-2 expression in brain endothelial cells.
  6. 신정섭;김영철 147
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    Six week-old ICR mice were divided into four groups including NC, RC, RR and RS, then they were injected with sun ginseng (RS), red ginseng (RR) and saline (RC) intraperitoneally as an amount of 60mg/kg body weight at 1 hour, 12 hours and 36 hours before the whole body irradiation with 6.5Gy of X-ray. And the mice were sacrificed at nine days after the irradiation. The RS group were significant increase in the weight of spleen (p<0.05) and the numbers of endogenous spleen colony (p<0.001) and WBC (p<0.05) especially neutrophils, lymphocytes and monocytes in comparison with the RC group. The RR group were significant increase in the numbers of endogenous spleen colony (p<0.01) and WBC (p<0.05) especially neutrophils, lymphocytes and eosinophils in comparison with the RC group. The RS group exhibited a more increase in the weight of spleen and the number of endogenous spleen colony than the RR group. The values of ALT (alanine transaminase) and AST (aspartate transaminase) were significantly elevated (p<0.05) by radiation and they were significantly decreased (p<0.05) in the RS group to the values of the NC group. The value of TBARS(thiobarbituric acid reactive substance) was significantly elevated (p<0.01) by radiation and it was significantly decreased (p<0.05) in the RS group. And the values of SOD (superoxide dismutase) and CAT (catalase) were significantly increased (p<0.05) in the RS group in comparison with the RC group. Taken together the above results, sun ginseng demonstrated the protective effects on hepatocytes and immune and hematopoietic cells in mice exposed to medium dose of irradiation, and those radioprotective effects were a little higher or similar to the red ginseng.
  7. 이철우;송상환;김현미;김학주;최경희;이문순 157
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    Tetrabromobisphenol A (TBBPA) is the most widely used BFR (brominated flame retardants) as a reactive flame retardant in printed circuit boards, and as additive applications in several types of polymers. The purpose of this study is to assess the adverse effects of TBBPA on the benthic amphipod (Hyalella azteca). Results on the acute toxicity of TBBPA using Hyalella azteca showed that NOEC and LOEC are 100mg/kg and 200mg/kg, respectively. In addition, when chronic toxicity of TBBPA was investigated at the concentration ranges between 0.01 to 100mg/kg, it was found that NOECs are $10mg/kg(fecundity){\sim}100mg/kg(viability)$, respectively. Significant fecundity inhibition was appeared at 100mg/kg of TBBPA, however, this concentration did not show severe adverse effect on weight increment. The values of PNEC were determined as 0.1mg/kg (fecundity) and 1mg/kg (lethal effect), respectively, using a safety factor suggested by EU and OECD.
  8. 오정민;여수정;김봉희;김상겸 165
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    Elevation of homocysteine levels is a risk factor for cardiovascular diseases and liver diseases. It has been reported that both streptozotocin-induced type I diabetic rats and obese type II diabetic rats have plasma total homocysteine lower than each control rats. We determined the effects of lean type II diabetes on homocysteine levels using type 2 diabetic Goto-Kakizaki rats. The concentrations of serum glucose were increased to ${\sim}two-fold$ of control levels and the total cholesterol levels were also increased in GK rats. Hepatic aspartate, histidine, threonine, alanine and methionine levels were significantly increased in GK rats. Plasma aspartate and glutamate levels were elevated, but threonine and arginine levels were decreased in GK rats. Plasma total homocysteine levels were not changed in GK rats, but hepatic total homocysteine levels were increased to ${\sim}three-fold$ of control levels. These results suggest that hepatic metabolism of sulfur-amino acid may be altered in diabetic condition.
  9. 류지성;김은경;문예련;김현미;김학주;최경희 171
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    Indigenous species means a species that is likely, due to historical presence, to occur at a specified site for some portion of its life span. Therefore, indigenous species can be useful as an indicator to assess environmental risk caused by hazardous chemicals in a specific site. So far a few toxicity studies using freshwater species which are indigenous to Korea have been carried out. In this study, a freshwater shrimp (Neocardina denticulata) indigenous to Korea was used for acute toxicity test of heavy metals. Neocardina denticulata were exposed to cadmium chloride $(CdCl_2)$, copper chloride $(CuCl_2)$ and zinc chloride $(ZnCl_2)$ using automatic flow-through system for 96 hours. The 96h LC50s were calculated as 0.043 $(0.042{\sim}0.045)mg\;CdCl_2/L,\;0.104(0.098{\sim}0.113)mg\; CuCl_2/L\;and\;2.021\;(1.633{\sim}2.594)mg\;ZnCl_2/L$. When compaired with some international standard species such as medaka(Oryzias latipes), Neocardina denticulata had high sensitivity. Therefore, this study suggested that Neocardina denticulata have possibilities for a sensitive test species to test heavy metal toxicity in aqua-system.
  10. 최민규;천만영 177
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    Gaseous organochlorine pesticides (OCPs : heptachlor epoxide, p, p'-DDE, ${\gamma}-HCH,\;{\alpha}-chlordane,\;{\gamma}-chlordane$ and trans-nonachlor) concentration was measured using PUF high volume sampler from June, 2000 to June, 2002 in the semi-rural atmosphere. The OCPs concentration in atmosphere, which is estimated by the slope (m) of Clausius-Clapeyron equation and phase-transition energy $({\Delta}H)$, was influenced by revolatilization from environmental matrix (soil, water and tree leaves) and a long range transportation of air mass. But the former affected OCPs concentration more than the latter. The degradation rate constants (k) of OCPs calculated using multiple regression analysis and revised standard temperature method were in good agreement each other. The value of k of ${\gamma}-HCH$ was very low as -0.0007, but the range of k of other components were $-0.00l8{\sim}-0.0038$. The half-life $({\tau})$ which was calculated by k of ${\gamma}-HCH$ was 2.6 years-the longest one, but that of heptachlor epoxide was in 0.5 year-the shortest one. $({\tau})\;of\;{\alpha}-chlordane,\;{\gamma}-chlordane$ and trans-nonachlor in technical chlordane was 1.0, 1.1 and 0.7 year respectively.
  11. 박은정;이종화;김대선;박광식 185
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    PM10 and PM2.5 in ambient air were collected in Seongbuk-gu area of Seoul for one year, from April 2005 to February 2006, and the concentration of PM-bound mercury was monitored. The annual concentrations of particles were $66.4{\pm}43.2{\mu}g/m^3\;(47.6{\pm}19.1{\mu}g/m^3-106.1{\pm}78.0{\mu}g/m^3)$ in PM10 and $37.2{\pm}20.4{\mu}g/m^3\;(28.0{\pm}23.4{\mu}g/m^3{\sim}42.7{\pm}21.4{\mu}g/m^3)$ in PM2.5, which is about 56% of PM10 concentration. The annual average concentrations of mercury were $0.125{\pm}0.078ng/m^3\;in\;PM10\;and\;0.141{\pm}0.080ng/m^3$ in PM2.5, respectively. In April of Asian dust season in Korea, mercury showed the highest concentration in both PM10 and PM2.5.