• Title, Summary, Keyword: Cell grouping

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The Change of Muscle Fiber by Aquatic Exercise on Rats Induced by Steroids Injection (스테로이드를 투여한 흰쥐에서 수중운동에 의한 근 섬유의 변화)

  • Yoon, Se-Won;Lee, Jung-Woo;Choi, Suk-Joo
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.1 no.2
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    • pp.21-30
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    • 2003
  • The purpose of this study was to know the effect of aquatic-exercise on muscle atrophy which induced by steroid injection. The forty-eight Sparague-Dawley adult male rats were assigned to the 4 groups; GroupI(distilled water injection), GroupII(steroid injection), GroupIII(distilled water injection and aquatic exercise), GroupIV(steroid injection and aquatic exercise). We observed their body weight, histological change by PAS stein. The results of this study were as follows; 1. After 2 weeks, the change of weights appeared that non-steroid injection groups increase weight and steroid injection groups decreased weight hasty. after 4 weeks, weights recovered from weight before test. It was possible to explain the change of weight by type II muscle fiber increase. 2. In histological change of muscle fibers, atrophy didn't observed in test group I, because type II muscle fibers were developed well. we observed not only injury of muscle fiber and muscle atrophy but specifically grouping type I muscle fiber in test group II. normal arrangement of muscle fibers were visible in test group and type II muscle fibers increased. we could observe muscle recovery because of type II muscle fibers increase in test group IV. therefore, it was seem that type II cell was recovering through aquatic exercise.

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Estimation and Implementation of the Uroflowmetry Using Load Cell (로드셀을 이용한 요류검사기의 구현 및 평가)

  • Jeong, Do-Un;Cho, Seong-Taek;Nam, Ki-Gon;Chung, Moon-Kee;Jeon, Gye-Rok
    • Journal of Sensor Science and Technology
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    • v.13 no.6
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    • pp.436-445
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    • 2004
  • In this study, a uroflowmetry system was developed to detect a voiding symptom conveniently at home or hospital. A implemented hardware was composed of mechanism and system circuit part, the software was developed to process uroflow data, graph display, extraction of parameter, and evaluation of congregate rate so as to analysis obtaining uroflow data. The following experiment was performed to evaluate an ability of classification and fitness. The curve pattern of uroflow was classified into each symptom. Various parameters were calculated in the curve pattern of each uroflow as follows. The parameters are MFR, AFR, VOL, VT, and FT. A significant difference among parameters was examined by a statistical analysis for extracted parameters between normal and abnormal experimental group. The uroflow data with the various symptom was divided into normal and abnormal group using fuzzy classifier. The result of the fuzzy classification using MFR and AFR was superior by 91.23 % than grouping evaluation including VOL.

How to design male hypothyroid hypogonadism model (갑상샘기능저하증에 따른 생식샘기능저하증 모델 정립을 위한 제언)

  • Yoon, Sang-Pil;Kim, Jung Woo
    • The Journal of Medicine and Life Science
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    • v.16 no.1
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    • pp.34-38
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    • 2019
  • Hypogonadism is a clinical syndrome that results in hormone deficiency and can be classified as 1) primary caused by the gonadal failure and 2) secondary by the hypothalamus-pituitary gland dysfunction and/or cardiometabolic complications. Recently the presence of thyroid hormone receptors in different testicular cell types was demonstrated, and thus thyroid dysfunctions would be another cause of secondary hypogonadism. Thus, we investigated the effects of perinatal hypothyroidism on hypogonadism in male Sprague-Dawley rats. Perinatal hypothyroidism was induced by daily administration of 0.05% 6-propyl-2-thiouracil (PTU) by tap water from gestation day 15, which were compared with negative control (PTU (-)) group. At postnatal day 28, hypothyroid pups were divided into 2 groups: PTU (+) group - continued PTU treatment and PTU (+/-) group - stopped PTU until postnatal day 49. Body weights, dehydrotesosterone (DHT), and testosterone levels were checked 2 and 3 weeks after grouping. Body weights were significantly decreased in PTU(+) and PTU(+/-) groups compared with PTU (-) group at postnatal day 28. 3 weeks later, PTU (+/-) group significantly gained weight compared with PTU (+) group. DHT and testosterone levels significantly decreased with PTU treatment, but increased 3 weeks after stopping PTU administration. Perinatal PTU-induced hypothyroid hypogonadism was sustained for 2 weeks after stopping PTU administration, but restored gonadal hormone levels 3 weeks after stopping PTU. These results suggest that researchers should design an experiment on hypothyroid hypogonadism based on the estimated period.

Anatomical Structures and Fiber Quality of Four Lesser-Used Wood Species Grown in Indonesia

  • MARBUN, Sari Delviana;WAHYUDI, Imam;SURYANA, Jajang;NAWAWI, Deded Sarip
    • Journal of the Korean Wood Science and Technology
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    • v.47 no.5
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    • pp.617-632
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    • 2019
  • This study aimed to investigate the anatomical structure and fiber quality of four lesser-used wood species namely Benuang (O. sumatrana), Duabanga (D. moluccana), Pisang Merah (H. hellwigii), and Terap (A. odoratissimus). This study evaluated its suitability for raw material in pulp and paper manufacturing. The anatomical structure was observed macro- and microscopically. Macroscopic structures were observed directly to the wood samples, while microscopic characteristics were observed through microtome specimens. Fiber dimension was measured through macerated specimens and fiber quality was analyzed following the Rachman and Siagian's method. Results showed that these four timber species have similarity in the indistinct growth ring, diffuse porous in a radial pattern, rounded solitary vessel outline, 1 to 3 cells of ray width, deposits within the rays, fiber length, and cell wall thickness. Differences were found on vessel diameter, vessel grouping, vessel frequency, tyloses existence, type of axial parenchyma, and ray height. Based on fiber length and its derived values, the wood fibers of all species studied are suitable for pulp and paper manufacturing. They belong to the II quality class. The produced pulp and paper would have good quality, especially in tensile, folding, and tear strength. To promote their utilization, silviculture aspect of these four species has to be well understood.

A Conditional Clustering Scheme for Hybrid NOMA in Millimeter Wave Communication System

  • Nguyen, Thanh Ngoc;Jeon, Taehyun
    • International journal of advanced smart convergence
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    • v.8 no.4
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    • pp.34-39
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    • 2019
  • Millimeter-wave (mmWave) and Non-orthogonal multiple access (NOMA) are expected to be the major techniques that lead to the next generation wireless communication. NOMA provides a high spectrum efficiency by sharing of spatial resources among users in the same frequency band. Meanwhile, millimeter-wave gives a huge underutilized bandwidth at extremely high frequency band (EHF) which covers 30GHz to 300GHz. These techniques have been proven in several recent literatures to achieve high data rates. The combination of NOMA and millimeter-wave techniques further improves average sum capacities, as well as reduces the interference compared to conventional wireless communication systems. In this paper, we focus on hybrid NOMA system working in millimeter-wave frequency. We propose a clustering algorithm used for a hybrid NOMA scheme to optimize the usage of wireless resources. The proposed clustering algorithm adds several conditions in grouping users and defining clusters to increase the probability of the successful superposition decoding process. The performance of the proposed clustering algorithm is investigated in hybrid NOMA system and compared with the conventional orthogonal multiple access (OMA) scheme.

Development of One Day-Ahead Renewable Energy Generation Assessment System in South Korea (우리나라 비중앙급전발전기의 하루전 출력 예측시스템 개발)

  • Lee, Yeon-Chan;Lim, Jin-Taek;Oh, Ung-Jin;N.Do, Duy-Phuong;Choi, Jae-Seok;Kim, Jin-Su
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.4
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    • pp.505-514
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    • 2015
  • This paper proposes a probabilistic generation assessment model of renewable energy generators(REGs) considering uncertainty of resources, mainly focused on Wind Turbine Generator(WTG) and Solar Cell Generator(SCG) which are dispersed widely in South Korea The proposed numerical analysis method assesses the one day-ahead generation by combining equivalent generation characteristics function and probabilistic distribution function of wind speed(WS) and solar radiation(SR) resources. The equivalent generation functions(EGFs) of the wind and solar farms are established by grouping a lot of the farms appropriately centered on Weather Measurement Station(WMS). First, the EGFs are assessed by using regression analysis method based on typical least square method from the recorded actual generation data and historical resources(WS and SR). Second, the generation of the REGs is assessed by adding the one day-ahead resources forecast, announced by WMS, to the EGFs which are formulated as third order degree polynomials using the regression analysis. Third, a Renewable Energy Generation Assessment System(REGAS) including D/B of recorded actual generation data and historical resources is developed using the model and algorithm predicting one day-ahead power output of renewable energy generators.

Analysis of Interactions in Multiple Genes using IFSA(Independent Feature Subspace Analysis) (IFSA 알고리즘을 이용한 유전자 상호 관계 분석)

  • Kim, Hye-Jin;Choi, Seung-Jin;Bang, Sung-Yang
    • Journal of KIISE:Computer Systems and Theory
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    • v.33 no.3
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    • pp.157-165
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    • 2006
  • The change of external/internal factors of the cell rquires specific biological functions to maintain life. Such functions encourage particular genes to jnteract/regulate each other in multiple ways. Accordingly, we applied a linear decomposition model IFSA, which derives hidden variables, called the 'expression mode' that corresponds to the functions. To interpret gene interaction/regulation, we used a cross-correlation method given an expression mode. Linear decomposition models such as principal component analysis (PCA) and independent component analysis (ICA) were shown to be useful in analyzing high dimensional DNA microarray data, compared to clustering methods. These methods assume that gene expression is controlled by a linear combination of uncorrelated/indepdendent latent variables. However these methods have some difficulty in grouping similar patterns which are slightly time-delayed or asymmetric since only exactly matched Patterns are considered. In order to overcome this, we employ the (IFSA) method of [1] to locate phase- and shut-invariant features. Membership scoring functions play an important role to classify genes since linear decomposition models basically aim at data reduction not but at grouping data. We address a new function essential to the IFSA method. In this paper we stress that IFSA is useful in grouping functionally-related genes in the presence of time-shift and expression phase variance. Ultimately, we propose a new approach to investigate the multiple interaction information of genes.

Refining prognostic stratification of human papillomavirus-related oropharyngeal squamous cell carcinoma: different prognosis between T1 and T2

  • Lee, Sumin;Lee, Sang-wook;Park, Sunmin;Yoon, Sang Min;Park, Jin-hong;Song, Si Yeol;Ahn, Seung Do;Kim, Jong Hoon;Choi, Eun Kyung;Kim, Su Ssan;Jung, Jinhong;Kim, Young Seok
    • Radiation Oncology Journal
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    • v.35 no.3
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    • pp.233-240
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    • 2017
  • Purpose: To validate the 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) TNM staging system for human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) and investigate whether a modified classification better reflects the prognosis. Materials and Methods: Medical records of patients diagnosed with non-metastatic HPV-related OPSCC between 2010 and 2016 at a single institution were retrospectively reviewed. HPV status was determined by immunohistochemical analysis of p16 and/or HPV DNA polymerase chain reaction (PCR). We reclassified TNM stage T0-1 and N0-1 as group A, T2-3 or N2 as B, and T4 or N3 as C. Survival analysis according to 8th AJCC/UICC TNM staging and the modified classification was performed. Results: Of 383 OPSCC patients, 211 were positive for HPV DNA PCR or p16. After exclusion, 184 patients were included in this analysis. Median age was 56 years (range, 31 to 81 years). Most primary tumors were in the palatine tonsil (148 tumors, 80%). The eighth AJCC/UICC TNM classification could not differentiate between stage I and II (p = 0.470) or II and III (p = 0.209). Applying modified grouping, the 3-year overall survival rate of group A was significantly higher than that of group B and C (98% vs. 91%, p = 0.039 and 98% vs. 78%, p < 0.001, respectively). Differentiation between group B and C was marginally significant (p = 0.053). Conclusion: The 8th AJCC/UICC TNM staging system did not clearly distinguish the prognosis of stage II from that of other stages. Including the T2N0-1 group in stage II may improve prognostic stratification.

Production of Retinol-binding Protein by Caprine Conceptus during the Time Period of Maternal Recognition of Pregnancy

  • Liu, K.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.7
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    • pp.962-967
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    • 2003
  • The purpose of the study were to characterize the proteins secreted by elongating caprine conceptus, to identify a group of low molecular weight proteins as retinol-binding protein (RBP), to identify RBP cell-specific localization in conceptus tissue, and to demonstrate that the conceptuses secreted continuously RBP during the time period maternal recognition of pregnancy. Caprine conceptuses were removed from the uterus between days 16 and 22 of pregnancy, the time period maternal recognition of pregnancy. Isolated conceptuses were cultured in a modified minimum essential medium in the presence of radiolabeled amino acids. Proteins synthesized and secreted into medium were analyzed by fluorography of two-dimensional polyacrylamide gel electrophoresis and fluorography. At least five proteins showed consistently a grouping of spots with characteristic location on two-dimensional gels. A major low molecular weight protein consisted of two major isoforms (pI 5.3-6.0) of similar molecular mass (21 kDa) was identified as RBP by using antiserum against RBP. Presence of RBP in conceptus culture medium and uterine flushings between days 16 and 22 of pregnancy were determined by immunoprecipitation and Western blotting using anti-RBP serum. In immunocytochemical study, strong immunostaining for RBP was localized in trophectoderm and endoderm of conceptus. These results clearly demonstrated that the caprine conceptus was active in protein synthesis as early as day 16 of pregnancy. Secretion of RBP by caprine conceptuses (days 16-22) coincident with the rapid transformation of the conceptus from a spherical blastocyst to a filamentous structure. Production of RBP by the elongating conceptuses may be indicative of an important role for conceptus RBP in the transport, availability and metabolism of retinol during maternal recognition of pregnancy.

Interference Canceller Wideband CDMA Systems for IMT-2000 (IMT-2000을 위한 Wideband CDMA시스템에서의 Interference Canceller)

  • 윤헌영;김낙명;문두영
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.8B
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    • pp.1371-1382
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    • 2000
  • IMT-2000 system is the third generation mobile communication system which aims at mobile multimedia services with global roaming. Like 2nd generation system, the IMT-2000 system is also under strong influence of interferences among active subscribers in the multiple access environment. That is, in multiple access environment, signals from one subscriber could interfere with others in the same cell or in the neighboring cells. The interference control in the IMT-2000 systems is much more difficult then the interference control in the 2ndgeneration CDMA cellular systems, since the transmitted power of a subcriber might be different that of others in the IMT-2000 system. In this paper, a parallel interference cancellation with traffic discrimination is proposed which can effectively cancel interferences by grouping the subscribers into several equi-power classes. As a conclusion, simulation results show that the proposed method outperforms the conventional partial PIC scheme in several aspects.

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