Journal of Pharmaceutical Investigation
- Volume 4 Issue 1_2
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- Pages.25-30
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- 1974
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Adsorption of Nalidixic Acid to Human Erythrocytes and Plasma
Nalidixic Acid의 혈구(血球) 및 혈장(血漿)에 대(對)한 흡착(吸着)
- Kim, Shin-Keun (College of Pharmacy, Seoul National University)
- 김신근 (서울대학교 약학대학)
- Published : 1974.03.20
Abstract
The adsorption of nalidixic acid on human erythrocytes was found to expressed by Freundlich's isotherm. The amount of adsorption of nalidixic acid on erythrocytes increased with an increase of pH. The adsorption of nalidixic acid on human plasma was found to expressed at Scatchard's equation by the equilibrium dialysis method. An influence of pH on adsorption of nalidixic acid to human plasma proteins was studies at pH 4-10. It was found that the degree of adsorption increase with the increase of pH from 4-6, but descreased above pH 9.
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