Korean Journal of Veterinary Research (대한수의학회지)
- Volume 36 Issue 1
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- Pages.65-74
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- 1996
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
Effect of superoxide anion in the regulation of artrial natriuretic peptide (ANP) secretion
심방이뇨호르몬의 분비조절에 있어서 superoxide anion의 영향
- Kang, Chang-won (College of Veterinary Medicine, Chonbuk National University) ;
- Kim, Nam-soo (College of Veterinary Medicine, Chonbuk National University) ;
- Lee, Ho-il (College of Veterinary Medicine, Chonbuk National University)
- Received : 1995.09.28
- Published : 1996.03.25
Abstract
Atrial Natriuretic Peptide(ANP) is a hormone with potent natriuretic, diuretic and relaxing properties of vascular smooth muscle. Specific chemical modulator responsible for the ANP secretion has not yet been found. Although atrial stretch of stretch-release is to be a major stimulus for the secretion of ANP, the precise mechano-molecular transduction mechanism responsible for its evoked secretion remains to be elucidated. It is interested to clarify the effect of superoxide anion in the stretch-induced ANP secretion. In order to investigate the effectg of