Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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Study on Antioxidant Potency of Cuscutae Semen, Psoraleae Fructus, Cnidii Fructus and Epimedii Herba by DPPH Method

DPPH 방법을 통한 토사자, 보골지(補骨脂), 사상자(蛇床子), 음양곽(淫羊藿)의 항산화 활성에 대한 연구

  • Oh, Myung-Sook (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Do-Rim (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kang, Ji-Ung (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, San-Woong (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Yu, Tae-Weon (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Park, Jung-Yeul (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Dong-Min (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Park, Wan-Su (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University) ;
  • Chang, Mun-Seog (Dept. of Medicine, Division of Newborn Medicine, Children's Hospital and Harvard Medical School) ;
  • Park, Soo-Yeon (Research institute of Physical education, Kyung Hee Univ.) ;
  • Park, Seong-Kyu (Dept. of Prescriptionology, College of Oriental Medicine, Kyung Hee University)
  • 오명숙 (경희대학교 한의과대학 방제학교실) ;
  • 김도림 (경희대학교 한의과대학 방제학교실) ;
  • 강지웅 (경희대학교 한의과대학 방제학교실) ;
  • 김산웅 (경희대학교 한의과대학 방제학교실) ;
  • 유태원 (경희대학교 한의과대학 방제학교실) ;
  • 박정열 (경희대학교 한의과대학 방제학교실) ;
  • 김동민 (경희대학교 한의과대학 방제학교실) ;
  • 박완수 (경희대학교 한의과대학 방제학교실) ;
  • 장문석 (하버드대학교 의과대학 소아병원) ;
  • 박수연 (경희대학교 체육과학연구소) ;
  • 박성규 (경희대학교 한의과대학 방제학교실)
  • Published : 2005.12.31
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Abstract

The present study was conducted to compare antioxidant activity of Cuscutae Semen, Psoraleae Fructus, Cnidii Fructus and Epimedii Herba by DPPH radical scavenging activity. The extract was studied using diphenyl-picryl-hydrazyl (DPPH) for DPPH method. DPPH radical scavenging activity was measured after. .10, 20 and 30 minutes. The extract was tested by 1, 5, 10, 50, 100, 500 and $1000{\mu}g/ml$ concentrations. The results showed that the extract scavenged DPPH radical with time-dependent manner. Also, the extract showed dose-dependent DPPH radical scavenging activity. The extract of Cuscutae Semen, Psoraleae Fructus, Cnidii Fructus and Epimedii Herba scavenged DPPH radical with the IC50 being 2.7, 3.2, 2.9 and 1.1 mg/ml, respectively. In conclusion, the extract of Epimedii Herba, Cuscutae Semen, Cnidii Fructus and Psoraleae Fructus have antioxidant activity for the treatment of male sterility.

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