Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
권호 표지

Antioxidant and antitumor activities of ethanol extracts from the fruiting body of Phellinus gilvus grown in oak and artificial sawdust

참나무 원목 및 톱밥에서 재배된 마른진흙버섯 자실체의 에탄올 추출물에 대한 항산화 및 항암활성

  • Hwang, Mi-hyun (College of Veterinary Medicine, Kyungpook National University) ;
  • Kim, Young-hoan (Gyeongbuk Veterinary Service Laboratory) ;
  • Kim, Kil-soo (College of Veterinary Medicine, Kyungpook National University) ;
  • Kim, Tae-wan (College of Veterinary Medicine, Kyungpook National University) ;
  • Jo, Woo-sik (Gyeongbuk Agricultural Technology Administration) ;
  • Choi, Sung-guk (Gyeongbuk Agricultural Technology Administration) ;
  • Kim, Jong-choon (College of Veterinary Medicine, Chonnam National University) ;
  • Park, Seung-chun (College of Veterinary Medicine, Kyungpook National University)
  • 황미현 (경북대학교 수의과대학) ;
  • 김영환 (경북가축위생시험소) ;
  • 김길수 (경북대학교 수의과대학) ;
  • 김태완 (경북대학교 수의과대학) ;
  • 조우식 (경상북도농업기술원 환경농업연구과) ;
  • 최성국 (경상북도농업기술원 환경농업연구과) ;
  • 김종춘 (전남대학교 수의과대학) ;
  • 박승춘 (경북대학교 수의과대학)
  • Accepted : 2005.02.28
  • Published : 2005.06.30
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Abstract

The purpose of this study is to examine the elemental compositions, antioxidant and antitumor activity of water, 20%, 40%, 60%, and 80% ethanol extracts obtained from the fruiting body of Phellinus gilvus. In electron donating ability test, the strong activities more than 70% were observed in $80{\mu}g/ml$ of 20%, 40%, 60% and 80% ethanol extracts from the fruiting body of P. gilvus grown in oak and sawdust. The antitumor activity was evaluated by sulforhodamine B (SRB) in terms of cell survival level. The tumor cells (sarcoma 180) were treated with various ethanol extracts (water, 20, 40, 60 and 80%). The results showed that all extracts inhibited proliferation showing a dose-dependent manner against tumor cells.

Keywords

References

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