Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Relation between Subjective Symptoms and Rhinolaryngoscopic Findings or Sputum Eosinophilia in Chronic Cough Patients

만성기침 환자의 주관적 증상과 비후두경 소견 및 객담 호산구 증가증과의 관련성

  • Kim, Hyun-Kuk (Department of Pulmonary and Critical Care Medicine, Haeundae Paik Hospital, Inje University College of Medicine) ;
  • Choi, Eun-Young (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jae-Seung (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Bae, Yun-Jeong (Department of Allergy, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Song, Jin-Woo (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Tae-Bum (Department of Allergy, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Cho, You-Sook (Department of Allergy, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Moon, Hee-Bom (Department of Allergy, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Sang-Do (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Oh, Yeon-Mok (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 김현국 (인제대학교 의과대학 해운대백병원 호흡기내과학교실) ;
  • 최은영 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 이재승 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 배윤정 (울산대학교 의과대학 서울아산병원 알레르기내과학교실) ;
  • 송진우 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 김태범 (울산대학교 의과대학 서울아산병원 알레르기내과학교실) ;
  • 조유숙 (울산대학교 의과대학 서울아산병원 알레르기내과학교실) ;
  • 문희범 (울산대학교 의과대학 서울아산병원 알레르기내과학교실) ;
  • 이상도 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 오연목 (울산대학교 의과대학 서울아산병원 호흡기내과학교실)
  • Received : 2010.08.11
  • Accepted : 2010.10.03
  • Published : 2010.11.30
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Abstract

Background: Rhinolaryngoscopy and sputum examination are popular tests for the evaluation of chronic cough. Little is known about the relationship between symptoms and rhinolaryngoscopic findings or sputum eosinophilia in chronic cough patients. Methods: One hundred patients, who had chronic cough with normal chest radiography and who also had undergone both rhinolaryngoscopy and induced sputum analysis, were reviewed retrospectively. Eleven associated symptoms of chronic cough were asked; postnasal drip (PND) and laryngopharyngeal reflux (LPR) were examined by rhinolaryngoscopy. Induced sputum analysis was performed for evaluation of sputum eosinophilia. Cross tabulation analyses with chi-square tests were used to evaluate the relationship between symptoms and objective findings. Results: The most frequent symptom was sputum (70%). The prevalence of PND and LPR on rhinolaryngoscopy were 56% (56/100) and 25.6% (22/86), respectively. Sputum eosinophilia was observed in 23 (23.7%) of 97 patients. The dyspnea (p=0.001), sputum (p=0.003), nasal obstruction (p=0.023), and postnasal drip sense (p=0.025) were related with PND on rhinolaryngoscopy. LPR on rhinolaryngoscopy was not related with any symptoms. Dyspnea (p=0.003), wheezing (p=0.005), nasal obstruction (p=0.013), and belching (p=0.018) were related with sputum eosinophilia. Conclusion: Any symptoms might not be related with LPR on laryngoscopy. Some symptoms might be related with PND on rhinoscopy or with sputum eosinophilia.

Keywords

References

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