DOI QR코드

DOI QR Code

An Arbitrary Waveform 16 Channel Neural Stimulator with Adaptive Supply Regulator in 0.35 ㎛ HV CMOS for Visual Prosthesis

  • Seo, Jindeok (Department of Electronics, Chungnam National University) ;
  • Lim, Kyomuk (Department of Electronics, Chungnam National University) ;
  • Lee, Sangmin (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Ahn, Jaehyun (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Hong, Seokjune (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Yoo, Hyungjung (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Jung, Sukwon (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Park, Sunkil (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Cho, Dong-Il Dan (ASRI/ISRC, School of Electrical Engineering and Computer Science, Seoul National University) ;
  • Ko, Hyoungho (Department of Electronics, Chungnam National University)
  • Received : 2012.06.05
  • Published : 2013.02.28

Abstract

We describe a neural stimulator front-end with arbitrary stimulation waveform generator and adaptive supply regulator (ASR) for visual prosthesis. Each pixel circuit generates arbitrary current waveform with 5 bit programmable amplitude. The ASR provides the internal supply voltage regulated to the minimum required voltage for stimulation. The prototype is implemented in $0.35{\mu}m$ CMOS with HV option and occupies $2.94mm^2$ including I/Os.

Keywords

References

  1. K. Chen, Z. Yang, L. Hoang, J. Weiland, M. Humayun, and W. Liu, "An Integrated 256- Channel Epiretinal Prosthesis," Solid-State Circuits, IEEE Journal of, Vol. 45, No. 9, pp. 1946-1956, Sep., 2010. https://doi.org/10.1109/JSSC.2010.2055371
  2. P. Livi, F. Heer, U. Frey, D. J. Bakkum, and A. Hierlemann, "Compact Voltage and Current Stimulation Buffer for High-Density Microelectrode Arrays," IEEE Transactions on Biomedical Circuits and Systems, Vol. 4, No. 6 , pp. 372-378, Dec., 2010. https://doi.org/10.1109/TBCAS.2010.2080676
  3. I. Kim, J. Song, Y. Zhang, T. Lee, T. Cho, Y. Song, D. Kim, S. Kim, and S. Hwang, "Biphasic electric current stimulates proliferation and induces VEGF production in osteoblasts," Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1763, No. 9 , pp. 907-916, Sep., 2006.
  4. T. Tokuda, K. Hiyama, S. Sawamura, K. Sasagawa, Y. Terasawa, K. Nishida, Y. Kitaguchi, T. Fujikado, Y. Tano, J. Ohta, "CMOS-Based Multichip Networked Flexible Retinal Stimulator Designed for Image-Based Retinal Prosthesis," Electron Devices, IEEE Transactions on, Vol. 56, No. 11 , pp. 2577-2585, Nov., 2009. https://doi.org/10.1109/TED.2009.2030552
  5. L. Theogarajan, "A Low-Power Fully Implantable 15-Channel Retinal Stimulator Chip," Solid-State Circuits, IEEE Journal of, Vol. 43, No. 10 , pp. 2322-2337, Nov., 2008. https://doi.org/10.1109/JSSC.2008.2004331
  6. M. Ortmanns, A. Rocke, M. Gehrke, H. Tiedtke, "A 232-Channel Epiretinal Stimulator ASIC," Solid-State Circuits, IEEE Journal of, Vol. 42, No. 12 , pp. 2946-2959, Dec., 2007. https://doi.org/10.1109/JSSC.2007.908693
  7. E. Noorsal, K. Sooksood, H. Xu, R. Hornig, J. Becker, M. Ortmanns, "A Neural Stimulator Frontend With High-Voltage Compliance and Programmable Pulse Shape for Epiretinal Implants," Solid-State Circuits, IEEE Journal of, Vol. 47, No. 1, pp. 244-256, Jan., 2012. https://doi.org/10.1109/JSSC.2011.2164667
  8. D. R. Merrill, M. Bikson, and J. G. Jefferys, "Electrical stimulation of excitable tissue: Design of efficacious and safe protocols," Journal of Neuroscience Methods, Vol. 141, pp. 171-198, Feb., 2005. https://doi.org/10.1016/j.jneumeth.2004.10.020