Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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A Study on the Cosmetic Preservative Effects of Cornus officinalis seed Extracts

산수유 종자 추출물의 화장품 방부효능에 관한 연구

  • Yang, Jae-Chan (Mokwon University, College of Sciences & Technology, Division of Biomedicinal & Cosmetics)
  • 양재찬 (목원대학교 테크노과학대학 생의약화장품학부)
  • Received : 2016.02.22
  • Accepted : 2016.06.20
  • Published : 2016.06.30
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Abstract

To evaluate the possibility as a natural preservative of Cornus officinalis seed extracts, we investigated the anti-microbial activity and preservation effect of cosmetics. Cornus officinalis seed extracted with 1,3-Butylene Glycol(1,3-BG) and Ethanol(EtOH). As a result, Cornus officinalis seed extracts showed anti-microbial activity at Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes and Cornus officinalis seed 1,3-BG extracts(COS-A) showed $26.7{\pm}4.0mm$ clear zone at the $1000.0{\mu}l/ml$. Minimum inhibitory concentration of S. epidermidis was observed at Cornus officinalis seed EtOH extracts(COS-B) $25.0{\mu}l/ml$. The result of challenge test for preservation effect on cosmetics, S. aureus and S. epidermidis was 100% eliminated from emulsion containing COS-A and COS-B after 7 days. These results suggest that Cornus officinalis seed extracts may have possibility as the natural preservative instead of synthetic perservative on cosmetics.

산수유 종자 추출물의 천연 방부제로서 가능성을 평가하기 위하여 항균활성 및 화장품 방부 효능 평가를 실시하였다. 산수유 종자는 각각 1,3-부틸렌글리콜과 에탄올을 이용하여 추출하였다. Paper disc method로 항균활성을 평가한 결과 Staphylococcus aureus, Staphylococcus epidermidis와 Propionibacterium acnes에서 항균활성이 나타났으며 산수유 종자 1,3-부틸렌글리콜 추출물(COS-A)이 여드름균에대해 $26.7{\pm}4.0mm$로 가장 높았다. 최소저해농도(MIC) 측정 결과 산수유 종자 에탄올 추출물(COS-B)이 가장 낮은 농도에서 S. epidermidis균의 생장을 억제하였다. 에멀션에서의 방부효능 평가를 위해 Challenge test를 실시한 결과 COS-A와 COS-B를 첨가한 에멀션에서 균 접종 7일 후 피부상재균이 100% 사멸되었다. 이러한 결과는 산수유 종자 추출물이 화장품에서 합성방부제를 대체할 천연 방부제로서 가능성이 있을 것으로 사료된다.

Keywords

References

  1. 서경희(2005). 화장품과 미생물 서울:화장품신문사.
  2. S. R. Hwang, J. O. Nam, B. J. Lee, W. H. Song, C, S, Lee. Recent Emulsion Technology in Cosmetics. KSBB Journal. 27(4), 207 (2012). https://doi.org/10.7841/ksbbj.2012.27.4.207
  3. H. S. Cho, S. W. Kang, J. H. Kim, M. J. Choi, H. W. Yu, Euteum Park, H. S. Chun, Antioxidant and Antimicrobial Activities of Combined Extracts of Galla rhois, Achyranthes japonica Nakai, Terminalia chebula Retz and Glycyrrhiza uralenesis. KSBB Journal. 29(1), 29 (2014). https://doi.org/10.7841/ksbbj.2014.29.1.29
  4. J. H. Kim, E. J. Do, Guemsan Lee. Investigation of Anti-microbial Activity of Herbal Medicines Used as Natural Preservatives Based on the Analysis of Papers and Patents. J. Physiol & Pathol Korean Med. 29(1), (2015).
  5. M. S. Ryu, J. K. Kim, N. K. Kim. Growth of Pseudomonas aeruginosa in Cosmetics(Emulsion-type) and the Effect of Antiseptics. Korean J. Biotechnol. Bioeng. 7(2), 118 (1992).
  6. M. S. Yoo. Effect of antiseptics for prevention of microbial contamination in cosmetics. Chemical Engineering. Sung Kyun Kwan Unversity. (1990).
  7. E. M. Cho, J. T. Bae, H. B. Pyo, G. S. Lee. Antimicrobial Plant Extracts as an Alternative of Chemical Preservative: Preservative Efficacy of Terminalia chebula, Rhus japonica (gallut) and Cinnmomum cassia Extract in the Cosmetic Formular. J. Soc. Cosmet. Scientists Korea. 34(4), 325 (2008).
  8. J. E. Ku, H. S. Han, J. H. Song. The Recent Trend of the Natural Preservative Used in Cosmetics. Kor. J. Aesthet. Cosmetol. 11(5), 835 (2013).
  9. H. S. Ahn, W. H. Nah, J. E. Lee, Y. S. Oh, M. C. Gye. Toxicity and Endocrine Disrupting Effect of Parabens. Korean J. Environ. Biol. 27(4), 323 (2009).
  10. S. H. Jeong. A Review Safety Evaluations of Cosmetic Preservatives. Kor. J. Aesthet. Cosmetol. 11(5), 827 (2013).
  11. S. H. Hwang, C. H. Park. Preservation of Cosmetics By Ethanol Extract of Scutellaria baicalensis GEORGE. KSBB Journal. 24(4), 347 (2009).
  12. E. Y. Choi, J. S. Lee, Y. S. Choe, T. B. Choe. Study on Antimicrobial Activity of Natural Preservatives and Effect of Cosmetic Formulation on Antimicrobial Activity. J. Industrial Science and Technology. Kon-Kuk University. 31, 11 (2006).
  13. Y. K. Park, W. K. Whang, I. H. Kim. The Antidiabetic Effects of from Cornus officinalis Seed. Chung-Ang J. Pharm. Sci. 9, 5 (1995).
  14. K. I. Seo, S. W. Lee, K. H. Yang. Antimicrobial and Antioxidative Activities of Corni Fructus Extracts. Korean J. Postharvest Sci. Technol. 6(1), 99 (1999).
  15. Y. H. Jeon, M. H. Park, Meera Kim. Antibacterial Activity of the Ethanol Extract from Cornus officinalis against Some Bacteria Related to Foodborne Illness and Food Spoilage. J. East Asian Soc Dietary Life. 22(5), 692 (2012).
  16. H. J. Jeon, M. J. Kim. Comparative studies on nutrients in Lycii Fructus and Corni Fructus by the different Drying Methods. Sook Myung Womens University. 10, 81 (1995).
  17. C. H. Park, N. S. Soeng, S. T. Lee, K. B. Youn, S. G. Son. Studies on Multiplication of Cornus officinalis by in vitro Culture. Korean J. Medical Crop Sci. 1(1), 63 (1993).
  18. S. O. Lee, S. M. Han, H. M. Kim, S. K. Jeung, J. Y. Choi, I, J, Kang. Chemical Components and Antimicrobial Effects of Corni fructus. J. Korean Soc Food Sci Nutr. 35(7), 891 (2006). https://doi.org/10.3746/jkfn.2006.35.7.891
  19. Mann. C. M. and J. L. Markham. 1998. A new method for determining the minimum inhibitory concentration of essential oils. J. Appl. Microbiol. 84, 538-544 (1998). https://doi.org/10.1046/j.1365-2672.1998.00379.x
  20. Farrinton. J. K. E. L. Martz. S. J. Wells. C. C. Ennis. J. Holder. J. W. Levchu. K. E. Avis. P. S. Hoffman, A. D. Hitchins. and J. M. Madden. Ability of laboratory methods to predict in-use efficacy of antimicrobial preservatives in an experimental cosmetic, Appl. Environ. Microbiol. 60, 4553-4558 (1994),
  21. Y. D. Kim, H. K. Kim, K. J. Kim. Antimicrobial Activity of Solvent Fraction from Cornus officinalis. J. Korean Soc. Food Sci. Nutr. 32(6), 829-832 (2003). https://doi.org/10.3746/jkfn.2003.32.6.829
  22. J. S. Ko. Antimicrobial Coating Agent. J. of Korean Oil Chemists' Soc., 30(1), 96 (2013). https://doi.org/10.12925/jkocs.2013.30.1.096
  23. J. M. Lee, S. S. Heo. Isolation and Identification of Antifungal Compounds from Eugenia caryophyllata Extracts. J. of Korean Oil Chemists' Soc., 31(4), 740 (2014). https://doi.org/10.12925/jkocs.2014.31.4.740
  24. W. G. Cho, H. J. Kim. Microbiological Effects of Xanthorrhizol against Candida albicans. J. of Korean Oil Chemists' Soc., 27(1), 37 (2010).

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