The purpose of this study was to identify factors influencing learning satisfaction of nursing students in online non-face-to-face classes during COVID-19 pandemic. 138 undergraduate nursing students were recruited from C nursing colleges of C city in Gyungnam. Data was collected using a self-reported online-questionnaire from 5 January to 18 January, 2022. Collected data were analyzed by SPSS/WIN 27.0 program using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and multiple regression. Factor influencing learning satisfaction among undergraduate nursing students on online non-face-to-face classes during COVID-19 pandemic were teaching presence(presence of teacher)(𝛽=.43, p<.001), instructional quality(content qualities)(𝛽=.41, p<.001), Satisfaction of nursing major(satisfaction)(𝛽=.13, p<.001). instructional quality(interface)(𝛽=.12, p=.036), which explained about 85.3% of total variance(F=192.78, p<.001). Therefore, in order to improve class satisfaction in online non-face-to-face classes, it is necessary to operate classes that prioritize the presence of teacher so that learners can recognize and trust the presence of teacher by passionately professional performing. And, among instructional quality, we should be strengthen the usefulness of learning materials, content factors related to tests and assignments, and strive to improve satisfaction of nursing major. In addition, it is necessary to prepare and operate classes that fully consider the interface factors related to the manual composition and system convenience for online classes among the quality factors of classes.