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Comparison Study for Analgesic Effects of Electroacupuncture on Surgical Ankle Sprain Model Classified as Grade 3 in Rats

수술적 방법으로 유도된 3단계 고도(高度) 발목염좌 모델에서 혈위(穴位)에 따른 전침효과의 비교

  • Yang, Seung-Bum (Department of Meridian & Acupoint, College of Korean Medicine, Wonkwang University) ;
  • Sohn, In-Chul (Department of Meridian & Acupoint, College of Korean Medicine, Wonkwang University) ;
  • Lee, Sung-Ho (Department of Sports and Leisure Studies, Yewon Arts University) ;
  • Cho, Sang-Hoon (Institute of Continuing Education, Myongji University) ;
  • Kim, Jaehyo (Department of Meridian & Acupoint, College of Korean Medicine, Wonkwang University)
  • 양승범 (원광대학교 한의과대학 경혈학교실) ;
  • 손인철 (원광대학교 한의과대학 경혈학교실) ;
  • 이성호 (예원예술대학교 생활체육과) ;
  • 조상훈 (명지대학교 사회교육원) ;
  • 김재효 (원광대학교 한의과대학 경혈학교실)
  • Received : 2013.02.27
  • Accepted : 2013.03.18
  • Published : 2013.03.27

Abstract

Objectives : The purpose of this study was to determine whether electroacupuncture(EA) is effective in reducing pain on the severe ankle sprain classified as grade 3 in rats. Methods : The severe(grade 3) ankle sprain model was induced surgically by ankle ligament injury(the anterior talofibular, the calcaneofibular and the posterior talofibular) in the Sprague-Dawley rats(180~250 g). The effects of EA on weight bearing forces(WBR) of the affected foot were examined in a rat model of ankle sprain. EA was applied to either SI6, ST37, GB34, GB39 or GB42 acupoints by trains of electrical pulses(2 Hz, 1 ms pulse width, 2 mA intensity) for 15 min. Results : Cutting of the lateral ankle ligament complex produced the severe ankle sprain symptoms as grade 3. EA of the contralateral SI6 resulted in more analgesic effect than one of ipsilateral SI6 even though there was significant effect. EA of the ipsilateral GB34 and GB39 produced potent analgesic effects on the surgical ankle sprained pain behaviors. However, there were no significant analgesic effects in the contralateral GB34 and GB39 EA groups. In addition, both side of ST37 and GB42 did not result in analgesic effect on the surgical ankle sprained rat. Conclusions : The data suggest that EA induced analgesia shows point specificity on the severe ankle sprained pain model classified as grade 3.

Keywords

References

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