Fig. 1. Isolation of (immuno-stimulating) polysaccharide (KAV- 0) isolated from Korean apple vinegars (A), and elution pattern and MW-determination of KAV-0 on HPSEC (B).
Fig. 2. Effect of KAV-0 on viabilities of murine peritoneal macrophages, RAW 264.7 and B16-BL6 melanoma cells.
Fig. 3. Effect of KAV-0 on cytokines and nitric oxide production by RAW 264.7 cells. RAW 264.7 cells were treated with indicated concentrations of KAV-0 for 24 hr.
Fig. 4. Effect of KAV-0 on cytokines and nitric oxide production by murine peritoneal macrophage in vitro.
Fig. 5. Effect of KAV-0 on cytolytic activity of NK cells ex vivo.
Fig. 6. Inhibitory effect of KAV-0 on lung metastasis produced by i.v. inoculation of B16-BL6 melanoma cells.
Table. 1. Chemical properties of KAV-0 isolated from apple vinegar