Purpose: The purpose of this study is to identify the factors influencing COVID-19 infection prevention behavior of nursing students. Methods: Data collection is from December 17 to October 22, 2021. One hundred and ninety-seven nursing students participated in this study. Data were analyzed using an independent t-test, ANOVA, correlation coefficient, scheffé test, and multiple regression analysis. Results: COVID-19 knowledge (r=.49, p<.001), attitude (r=.41, p<.001), and COVID-19 risk perception (r=.40, p<.001) were related to COVID-19 infection prevention behaviors. The factors influencing COVID-19 preventive behaviors were identified as knowledge (𝛽=.28, p<.001), attitude (𝛽=.25, p<.001), risk perception (𝛽=.18, p=003), 2th grade (𝛽=.19, p=.011), 3th grade (𝛽=.21, p=.006), 4th grade (𝛽=.20, p=.008), and gender (𝛽=.12, p=.033). Conclusion: The results of this study can be used for the development of health policies suitable for community infectious disease prevention behaviors and the development of infectious disease educational intervention programs.